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Table 2 Univariate and multivariate analysis of factors associated with virological non suppression in CLWH on ART for a at least 6 months (N = 250)

From: HIV virological non-suppression and its associated factors in children on antiretroviral therapy at a major treatment centre in Southern Ghana: a cross-sectional study

 

Univariate analysis

Multivariate analysis

Factor

UOR (95% CI)

P value

AOR (95% CI)

P value

Sex of child

 

0.004*

 

0.041*

 Male

ref

   

 Female

2.52 1.35–4.67

 

2.51 1.04–6.07

 

Age category

 

0.342

 

0.138

 < 5 years

1.72 0.57–5.24

 

2.18 0.23–20.89

 

 5 to < 10 years

1.57 0.78 –3.17

 

2.84 1.01–8.05

 

 10 to 15 years

ref

 

ref

 

CD4+ Immune suppression status at study recruitment

 

< 0.001*

 

< 0.001*

 Severe

9.03 3.08–26.51

 

24.93 4.92–126.31

 

 Advanced

7.97 2.03–31.31

 

9.2 1.27–66.48

 

 Mild

3.65 1.35–9.9

 

3.75 0.91–15.4

 

 None

ref

 

ref

 

TB treatment in the past

 

0.122

 

0.006*

 No

ref

 

ref

 

 Yes

1.67 0.87–3.18

 

4.95 1.58–15.5

 

Current Drug

 

0.231

 

0.005*

 Efavirenz based

ref

 

ref

 

 Nevirapine based

1.79 0.9 – 3.52

 

7.93 2.26–27.86

 

 Second line drug

0.86 0.15–4.86

 

1.02 0.09–11.8

 

Pill count rate

 

0.012*

 

0.264

 Good adherence

ref

 

ref

 

 Fair adherence

0.3 0.1–0.93

 

0.43 0.11 – 1.69

 

 Poor adherence

1.93 0.92–4.03

 

1.65 0.54 – 5.01

 
  1. *: p < 0.05