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Table 1 Characteristics of patients associated with in-hospital mortality

From: Circulating lymphocyte subsets as promising biomarkers to identify septic patients at higher risk of unfavorable outcome

Variables

Overall

278 (100%)

Survivors

229 (82.4%)

Non survivors

49 (17.6%)

p

Age, years, mean (SD)

63.25 (19.65)

60.44 (19.81)

76.41 (12.28)

 < 0.001

Males/females, n (%)

171/107 (61.5/38.5)

151/78 (65.9/34.1)

20/29 (40.8/59.2)

0.001

Charlson Comorbidity Index

    

  ≤ 3, (%)

39.93

46.29

10.20

 

 4–6, (%)

36.69

33.19

53.06

 

  > 6, (%)

23.38

20.52

36.73

 

 Mean (SD)

4.23 (2.95)

3.85 (2.93)

6.0 (2.35)

 < 0.001

Comorbid condition

    

 Myocardial infarction history

5 (1.8)

4 (1.7)

1 (2.0)

 

 Peripheral disease

14 (5.0)

10 (4.4)

4 (8.2)

 

 Cerebro-vascular disease

110 (39.6)

88 (38.4)

22 (44.9)

 

 Dementia

23 (8.3)

9 (3.9)

14 (28.6)

 

 Chronic pulmonary disease

62 (22.3)

52 (22.7)

10 (20.4)

 

 Connective tissue disease

6 (2.2)

4 (1.7)

2 (4.1)

 

 Peptic ulcer disease

3 (1.1)

1 (0.4)

2 (4.1)

 

 Mild liver disease

27 (9.7)

24 (10.5)

3 (6.1)

 

 Diabetes without end-organ damage

63 (22.7)

52 (22.7)

11 (22.4)

 

 Hemiplegia

5 (1.8)

3 (1.3)

2 (4.1)

 

 Moderate or severe renal disease

49 (17.6)

38 (16.6)

11 (22.4)

 

 Diabetes with end-organ damage

5 (1.8)

4 (1.7)

1 (2.0)

 

 Tumor without metastasis

26 (9.4)

17 (7.4)

9 (18.4)

 

 Leukemia

3 (1.1)

1 (0.4)

2 (4.1)

 

 Lymphoma

3 (1.1)

1 (0.4)

2 (4.1)

 

 Moderate or severe liver disease

6 (2.2)

6 (2.6)

0 (0.0)

 

 Metastatic solid tumor

3 (1.1)

2 (0.9)

1 (2.0)

 

qSOFA, mean (SD)

1.30 (0.87)

1.16 (0.87)

1.96 (0.55)

 < 0.001

PCT, ng/dL, mean (SD)

20.7 (31.1)

17.4 (28.1)

36.5 (39.5)

 < 0.001

Positive blood culture, n (%)

137 (49.28)

113 (49.34)

24 (49.0)

0.96

Length of stay, mean (SD)

16.6 (11.6)

15.1 (10.0)

16.8 (11.9)

0.4

Infection

    

 Pneumonia

91 (32.7)

70 (30.6)

21 (42.9)

 

 Gastrointestinal infection

50 (18.0)

40 (17.5)

10 (20.4)

 

 Urinary tract infection (UTI)

39 (14.0)

35 (15.3)

4 (8.2)

 

 Skin and soft tissue infection

25 (9.0)

25 (10.9)

0 ( 0.0)

 

 Endocarditis

13 (4.7)

12 (6.3)

1 (2.0)

 

 Central venous catheter infection

4 (1.4)

4 (1.7)

0 (0.0)

 

 Pleuritis

4 (1.4)

2 (0.9)

2 (4.1)

 

 Peripherally inserted central catheter infection

3 (1.1)

2 (0.9)

1 (2.0)

 

 Wound infection

3 (1.1)

2 (0.9)

1 (2.0)

 

 Abscess

2 (0.7)

2 (0.9)

0 (0.0)

 

 Meningoencephalitis

2 (0.7)

2 (0.9)

0 (0.0)

 

 Osteomyelitis

2 (0.7)

2 (0.9)

0 (0.0)

 

 Unknown

40 (14.4)

31 (13.5)

9 (18.4)

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