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Table 3 Sensitivity and specificity of different cut-points of lymphocytes T-CD4 in predicting in-hospital mortality

From: Circulating lymphocyte subsets as promising biomarkers to identify septic patients at higher risk of unfavorable outcome

Variable

Sensitivity,

% (IQR)

Specificity,

% (IQR)

PPV,

% (IQR)

NPV,

% (IQR)

CD4 + T cells < 200/µL

55.1 (40.2–69.3)

77.7 (71.8–82.9)

35.6 (24.2–46.2)

89.9 (83.8–93.0)

CD4 + T cells < 250/µL

67.3 (52.5–80.1)

70.7 (64.4–76.5)

33.0 (23.9–43.1)

91.0 (85.8–94.8)

CD4 + T cells < 300/µL

81.6 (68.0–91.2)

64.2 (57.6–70.4)

32.8 (24.6–41.9)

94.2 (89.3–97.3)

CD4 + T cells < 350/µL

85.7 (72.8–94.1)

59.4 (52.7–65.8)

31.1 (23.4–39.6)

95.1 (90.2–98.0)

CD4 + T cells < 400/µL

87.8 (75.2–95.4)

52.0 (45.3–58.6)

28.1 (21.1–35.9)

95.2 (89.8–98.2)

CD4 + T cells < 450/µL

87.8 (75.2–95.4)

43.2 (36.7–49.9)

24.9 (18.6–32.0)

94.3 (88.0–97.9)

  1. PPV positive predictive value, NPV negative predictive value