Association between bacterial finding, antibiotic treatment and clinical course in patients with pharyngotonsillitis: a registry-based study in primary healthcare in Sweden

Table 2 Rapid Antigen Detection Test (RADT) for GAS result and antibiotic prescription in relation to outcomes

RADT for GAS¹	Antibiotics²	Pharyngotonsillitis	Complication		Peritonsillitis³		Tonsillectomy
RADT for GAS¹	Antibiotics²	30 d	30 d	60 d	30 d	60 d	90 d
Positive	All	791/8928 (8.9%)	136/8928 (1.5%)	211/8728 (2.4%)	33/8928 (0.37%)	37/8728 (0.42%)	23/8561 (0.27%)
	Antibiotics +	743/8528 (8.7%)	129/8528 (1.5%)	199/8338 (2.4%)	30/8528 (0.35%)	34/8338 (0.41%)	22/8182 (0.27%)
	Antibiotics −	48/400 (12%)	7/400 (1.8%)	12/390 (3.1%)	3/400 (0.75%)	3/390 (0.77%)	1/379 (0.26%)
	p	0.02	0.7	0.4	0.2†	0.2†	1†
Negative	All	369/4532 (8.1%)	78/4532 (1.7%)	104/4479 (2.3%)	30/4532 (0.66%)	34/4479 (0.76%)	13/4426 (0.29%)
	Antibiotics +	190/1965 (9.7%)	32/1965 (1.6%)	43/1939 (2.2%)	16/1965 (0.81%)	19/1939 (0.98%)	6/1918 (0.31%)
	Antibiotics −	179/2567 (7.0%)	46/2567 (1.8%)	61/2540 (2.4%)	14/2567 (0.55%)	15/2540 (0.59%)	7/2508 (0.28%)
	p	0.01	0.7	0.7	0.3	0.1	0.8

Rapid antigen detection test (RADT) for group A streptococci (GAS) and antibiotic prescription in relation to outcomes in patients where an RADT was performed on the same day as a visit to primary healthcare (n = 13 781)
^†Fisher’s exact test
¹Refers to RADTs performed on the same day as the index visit
²Refers to antibiotics approved by the Swedish Medical Products Agency for treating pharyngotonsillitis (see Methods section) prescribed on the same day as the index visit
³Patients with peritonsillitis are also included in “Complication”

ISSN: 1471-2334