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Table 2 Rapid Antigen Detection Test (RADT) for GAS result and antibiotic prescription in relation to outcomes

From: Association between bacterial finding, antibiotic treatment and clinical course in patients with pharyngotonsillitis: a registry-based study in primary healthcare in Sweden

RADT for GAS1 Antibiotics2 Pharyngotonsillitis Complication Peritonsillitis3 Tonsillectomy
30 d 30 d 60 d 30 d 60 d 90 d
Positive All 791/8928 (8.9%) 136/8928 (1.5%) 211/8728 (2.4%) 33/8928 (0.37%) 37/8728 (0.42%) 23/8561 (0.27%)
Antibiotics +  743/8528 (8.7%) 129/8528 (1.5%) 199/8338 (2.4%) 30/8528 (0.35%) 34/8338 (0.41%) 22/8182 (0.27%)
Antibiotics −  48/400 (12%) 7/400 (1.8%) 12/390 (3.1%) 3/400 (0.75%) 3/390 (0.77%) 1/379 (0.26%)
p 0.02 0.7 0.4 0.2† 0.2† 1†
Negative All 369/4532 (8.1%) 78/4532 (1.7%) 104/4479 (2.3%) 30/4532 (0.66%) 34/4479 (0.76%) 13/4426 (0.29%)
Antibiotics +  190/1965 (9.7%) 32/1965 (1.6%) 43/1939 (2.2%) 16/1965 (0.81%) 19/1939 (0.98%) 6/1918 (0.31%)
Antibiotics −  179/2567 (7.0%) 46/2567 (1.8%) 61/2540 (2.4%) 14/2567 (0.55%) 15/2540 (0.59%) 7/2508 (0.28%)
p 0.01 0.7 0.7 0.3 0.1 0.8
  1. Rapid antigen detection test (RADT) for group A streptococci (GAS) and antibiotic prescription in relation to outcomes in patients where an RADT was performed on the same day as a visit to primary healthcare (n = 13 781)
  2. Fisher’s exact test
  3. 1Refers to RADTs performed on the same day as the index visit
  4. 2Refers to antibiotics approved by the Swedish Medical Products Agency for treating pharyngotonsillitis (see Methods section) prescribed on the same day as the index visit
  5. 3Patients with peritonsillitis are also included in “Complication”