Table 2 Sensitivity and specificity data extracted from each study
Study | Sample size | True Positive | False Negative | False Positive | True Negative | Sensitivity | Sensitivity 95% CI Low | Sensitivity 95% CI High | Specificity | Specificity 95% CI Low | Specificity 95% CI High |
|---|---|---|---|---|---|---|---|---|---|---|---|
Iglὁi et al. [23] | 970 | NA | NA | NA | NA | 84.9 | 79.1 | 89.4 | 99.5 | 98.7 | 99.8 |
Berger et al. (Ag2) [15] | 535 | NA | NA | NA | NA | 85.5 | 78.0 | 92.1 | 100.0 | 99.1 | 100.0 |
Berger et al. (Ag1) [15] | 529 | NA | NA | NA | NA | 89.0 | 83.7 | 93.1 | 99.7 | 98.4 | 100.0 |
Abdelrazik et al. [12] | 310 | 81 | 107 | 0 | 122 | 43.1 | 36.2 | 50.2 | 100.0 | 97.0 | 100.0 |
Abdulrahman et al. [13] | 4183 | 602 | 131 | 30 | 3420 | 82.1 | 79.2 | 84.7 | 99.1 | 98.8 | 99.4 |
Albert et al. [14] | 412 | 43 | 11 | 0 | 358 | 79.6 | 67.1 | 88.2 | 100.0 | 98.9 | 100.0 |
Blairon et al. [16] † | 774 | 60 | 99 | 0 | 615 | 37.7† | 30.6† | 45.5† | 100.0 | 99.4 | 100.0 |
Bulilete et al. [17]* | 1369 | 100 | 40 | 2 | 1220 | 71.4 | 63.5* | 78.3* | 99.8 | 99.4* | 100.0 |
Chaimayo et al. [19]† | 454† | 64 | -4 | 4 | 390 | 106.7† | NA† | NA† | 99.0† | 97.4† | 99.6 |
Courtellemont et al. [20] | 248 | 117 | 4 | 0 | 127 | 96.7 | 91.8 | 98.7 | 100.0 | 97.1 | 100.0 |
Drevinek et al. [21] (Ag1) | 591 | 148 | 75 | 0 | 368 | 66.4 | 59.9 | 72.2 | 100.0 | 99.0 | 100.0 |
Drevinek et al. [21] (Ag2)* | 591 | 141 | 82 | 2 | 366 | 63.2* | 56.7 | 69.3 | 99.5 | 98.0 | 99.9 |
Gremmels et al. [22]† | 1575 | 152 | 50 | 0 | 1373 | 75.2† | 68.9† | 80.7† | 100.0 | 99.7 | 100.0 |
L.J. Krüger et al. [24] (2020) | 1108 | 92 | 14 | 1 | 1001 | 86.8 | 79.0 | 92.0 | 99.9 | 99.4 | 100.0 |
L.J. Krüger et al. [25] (2020) | 2417 | 50 | 20 | 85 | 2262 | 71.4 | 60.0 | 80.7 | 96.4 | 95.5 | 97.1 |
L.J. Krüger et al. [25] (2020) (Ag1) | 1263 | 36 | 11 | 9 | 1207 | 76.6 | 62.8 | 86.4 | 99.3 | 98.6 | 99.6 |
L.J. Krüger et al. [25] (2020) (Ag2) | 425 | 4 | 4 | 25 | 392 | 50.0 | 21.5 | 78.5 | 94.0 | 91.3 | 95.9 |
L.J. Krüger et al. [25] (2020) (Ag3) | 729 | 10 | 5 | 51 | 663 | 66.7 | 41.7 | 84.8 | 92.9 | 90.7 | 94.5 |
Linares et al. [26]† | 255 | 40 | 20 | 0 | 195 | 66.7† | 54.1† | 77.3† | 100.0 | 98.1 | 100.0 |
Masiá et al. [27]* | 913 | 118 | 78 | 0 | 709 | 60.2* | 53.2 | 66.8 | 100.0 | 99.5 | 100.0 |
Merino-Amador et al. [28] | 958 | 325 | 34 | 7 | 592 | 90.5 | 87.1 | 93.1 | 98.8 | 97.6 | 99.4 |
Moeren et al. [29]† | 352 | 122 | 1 | 0 | 334 | 99.2† | 95.5† | 99.9† | 100.0 | 98.9 | 100.0 |
Nalumansi et al. [30] | 262 | 63 | 27 | 13 | 159 | 70.0 | 59.9 | 78.5 | 92.4 | 87.5 | 95.5 |
Peto et al. [31] | 6954 | 155 | 42 | 22 | 6735 | 78.7 | 72.4 | 83.8 | 99.7 | 99.5 | 99.8 |
Porte et al. [32] | 127 | 77 | 5 | 0 | 45 | 93.9 | 86.5 | 97.4 | 100.0 | 92.1 | 100.0 |
Torres et al. [34] | 634 | 38 | 41 | 0 | 555 | 48.1 | 37.4 | 59.0 | 100.0 | 99.3 | 100.0 |
Veyrenche et al. [35]† | 45† | 13 | 32 | 0 | 0 | 28.9† | 17.7† | 43.4† | NA† | NA† | NA† |
Schwob et al. [33]† | 928 | 327 | 45 | 0 | 601 | 87.9† | 84.2† | 90.8† | 100.0 | 99.4 | 100.0 |