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Table 2 Univariate analyses with laboratory parameters in the outcomes in HIV/AIDS patients

From: Immunologic biomarkers, morbidity and mortality among HIV patients hospitalised in a Tertiary Care Hospital in the Brazilian Amazon

Laboratory tests

Death

Discharge

p

N = 17

N = 66

Hematological data (NVA)

 HIV-RNA copies/mLb

126,578 (3247–273,012)

25,258.5 (391.5–145,976.8)

0.590

 Lymphocytes (percent)a (25.0–40.0%)

20.5 (10.3)

27.4 (13.5)

0.055

 CD4-T cells/µLb (600 to 1500/mm3)

44 (7–232)

79 (30–198.2)

0.140

 CD8-T cells/µLb (200 to 800/mm3)

402 (198–776)

544.5 (359.2–1143.8)

0.312

 CD4/CD8 ratiob (1.0 and 4.0)

0.1 (0–0.4)

0.1 (0.1–0.3)

0.123

 Hemoglobin (13.0–18.0 g/dL)

9.3 (2.7)

10.8 (2.4)

0.165

 Leukocytesb (4500–11,000/mL)

4740 (3510–8600)

4215 (3275–5,757.5)

0.527

 Neutrophilsb (1800–7700/mL)

2660 (1679–3234)

3118 (2109–4907.5)

0.113

 Monocytesb (80–1100/mL)

249 (161–379)

329 (187.2–488.2)

0.370

 Eosinophilsb (40–550/mL)

2 (2–4)

4 (2.6–7)

0.030*

 Plateletsa (150,000–400,000 × 103/mL)

299,352.9 (207,630.4)

273,947.0 (132,454.6)

0.536

 MPVb (8.8 fL to 12.5 fL)

8.2 (7.8–8.8)

8.1 (7.4–8.7)

0.446

 PDWb (9.3 fL to 16.0 fL)

15.8 (13–18.7)

13.5 (11.2–16.5)

0.037*

Biochemistry parameters (NVA)

 Bilirubinb (< 1.0 mg/dL)

0.4 (0.2–0.9)

0.4 (0.3–0.7)

0.999

 Creatinineb (0.6–1.35 mg/dL)

1 (0.7–1.3)

0.8 (0.6–0.9)

0.069

 LDHb (120 and 246 U/uL)

435 (332–534)

367.5 (300.2–474.2)

0.159

 Gamma-glutamyltransferaseb,c

88 (42–203)

103.5 (57.8–290)

0.876

 Albuminb (3.5–5.0 g/dL)

3.4 (2.8–4)

3.8 (3.3–4.5)

0.129

 Alkaline phosphataseb (65.0–330.0 U/uL)

282 (200–459)

281 (201–386)

0.835

 Aspartate aminotransferaseb (2–38.0 U/uL)

44 (26–82)

34 (25–58)

0.280

 Alanine aminotransferaseb (2–44.0 U/uL)

31 (22–41)

43 (31–77)

0.038*

  1. NVA Normal values in adults, PDW Platelet distribution width, MPV Mean platelet volume, LDH lactate dehydrogenase
  2. aMean and standard
  3. bMedian (25th; 75th interquartile)
  4. cReferences values of Gamma-glutamyltransferase (men: 10 to 50 U/uL and women: 7 to 32 U/uL)
  5. *, **: p-value; statistically significant difference