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Table 2 Risk factors for disease progression in patients with COVID-19

From: Risk factors for disease progression in Japanese patients with COVID-19 with no or mild symptoms on admission

Factor

Univariate

Multivariate

OR (95% CI)

P value

OR (95% CI)

P value

Age (per 10 years)

1.495 (1.243–1.808)

 < 0.001

1.538 (1.219–1.949)

 < 0.001

Sex

2.494 (1.212–5.132)

0.013

  

Overweight (BMI ≥ 25)

4.108 (2.103–8.025)

 < 0.001

3.260 (1.463–7.265)

0.0038

Asthma

0.984 (0.371–2.606)

0.97

  

Hypertension

5.170 (2.577–10.37)

 < 0.001

  

Cardiovascular disease

2.919 (1.191–7.156)

0.019

  

Diabetes

3.594 (1.473–8.773)

0.0050

2.851 (1.056–7.698)

0.039

NLR

1.057 (0.970–1.153)

0.21

  

CRP

1.272 (1.132–1.430)

 < 0.001

  

LDH

1.010 (1.005–1.015)

 < 0.001

  

Creatinine

9.551 (2.327–39.20)

0.0017

  

Ferritin

1.003 (1.002–1.004)

 < 0.001

1.002 (1.001–1.004)

 < 0.001

D-dimer

1.009 (0.936–1.088)

0.81

  
  1. Risk factors associated with disease severity were analyzed using a logistic regression model. P < 0.05 was considered statistically significant
  2. OR odds ratio, CI confidence interval, BMI body mass index, NLR neutrophil-to-lymphocyte ratio, CRP C-reactive protein, LDH lactate dehydrogenase
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BMC Infectious Diseases

ISSN: 1471-2334

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