SNVs | Haplotype | Freq | Case, control frequencies | Chi-square | P-value | Pcorr valuea | OR (95%CI)b, P-value | OR (95%CI)c, P-value |
---|---|---|---|---|---|---|---|---|
rs662_rs854560 | AA | 0.391 | 0.318, 0.452 | 6.628 | 0.010 | 0.019 | 0.57 (0.37–0.88), 0.011 | Reference |
AT | 0.363 | 0.391, 0.340 | 0.998 | 0.318 | 0.629 | 1.22 (0.79–1.88), 0.366 | 1.60 (0.99–2.59), 0.057 | |
GA | 0.223 | 0.256, 0.196 | 1.812 | 0.178 | 0.374 | 1.40 (0.86–2.30), 0.179 | 1.83 (1.05–3.18), 0.031 | |
GT | 0.022 | 0.035, 0.012 | 2.121 | 0.145 | 0.304 | 3.72 (0.74–18.7), 0.088 | 5.09 (0.99–26.17), 0.032 | |
rs854560_rs705379 | AC | 0.392 | 0.372, 0.408 | 0.482 | 0.487 | 0.843 | 0.85 (0.56–1.31), 0.466 | Reference |
TT | 0.304 | 0.325, 0.286 | 0.611 | 0.435 | 0.803 | 1.22 (0.77–1.91), 0.396 | 1.26 (0.76–2.09), 0.365 | |
AT | 0.223 | 0.202, 0.240 | 0.735 | 0.391 | 0.756 | 0.81 (0.49–1.34), 0.415 | 0.94 (0.54–1.63), 0.816 | |
TC | 0.082 | 0.101, 0.066 | 1.508 | 0.219 | 0.491 | 1.54 (0.72–3.31), 0.263 | 1.64 (0.73–3.67), 0.225 | |
rs662_rs854560_rs705379 | ATT | 0.286 | 0.297, 0.276 | 0.189 | 0.663 | 0.997 | 1.13 (0.71–1.79), 0.611 | Reference |
AAC | 0.277 | 0.235, 0.312 | 2.628 | 0.105 | 0.372 | 0.69 (0.43–1.11), 0.123 | 0.70 (0.40–1.23), 0.214 | |
GAC | 0.115 | 0.138, 0.096 | 1.564 | 0.211 | 0.670 | 1.49 (0.77–2.85), 0.233 | 1.30 (0.63–2.69), 0.475 | |
AAT | 0.114 | 0.082, 0.140 | 2.961 | 0.085 | 0.314 | 0.55 (0.28–1.11), 0.093 | 0.54 (0.25–1.17), 0.115 | |
GAT | 0.109 | 0.119, 0.100 | 0.322 | 0.570 | 0.984 | 1.19 (0.61–2.31), 0.616 | 1.07 (0.51–2.24), 0.860 | |
ATC | 0.078 | 0.095, 0.064 | 1.172 | 0.279 | 0.794 | 0.49 (0.17–1.39), 0.171 | 1.30 (0.56–3.00), 0.541 | |
GTT | 0.018 | 0.028, 0.010 | 1.462 | 0.227 | 0.696 | 3.13 (0.60–16.4), 0.155 | 2.81 (0.52–15.2), 0.212 |