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Table 1 General characteristics of enrolled children

From: Real-life isoniazid and rifampicin plasma concentrations in children: a tool for therapeutic drug monitoring of tuberculosis

Patients characteristics

Latent TB

n = 26

Active TB

n = 19

All

n = 45

Sex

   

 Male

17/26 (65.4%)

15/19 (78.9%)

32/45 (71.1%)

 Female

9/26 (34.6%)

4/19 (21.1%)

13/45 (28.9%)

Age (months)—median [IQRs]

101 [64–187]

43 [22–134]

82 [38–148]

Reason for investigation

   

 Adoption/immigrant screening

11/26 (42.3%)

0/19

11/45 (24.4%)

 Household contact

12/26 (46.2%)

6/19 (31.6%)

18/45 (40%)

 Symptomatic

0/26

11/19 (57.9%)

11/45 (24.4%)

 Not household contact

3/26 (11.5%)

2/19 (10.5%)

5/45 (11.2%)

Ethnicity

   

 Caucasian

15/26 (57.7%)

10/19 (52.6%)

25/45 (55.5%)

 African

0/26

4/19 (21%)

4/45 (8.9%)

 Asian

3/26 (11.5%)

2/19 (10.5%)

5/45 (11.1%)

 South American

8/26 (30.8%)

3/19 (15.8%)

11/45 (24.5%)

Type of TB

   

 Microbiological confirmed

–

9/19 (47.3%)

–

 No microbiological confirmed

–

11/19 (57.9%)

–

  1. TB tuberculosis; IQR interquartile range