Table 1 Demographic and clinical characteristics of patients hospitalized due to invasive pneumococcal disease (IPD)
From: Invasive pneumococcal disease burden in hospitalized adults in Bogota, Colombia
Patients characteristics | All patients (n = 310) | Pneumonia (n = 186) | Meningitis (n = 58) | Others (n = 66) |
|---|---|---|---|---|
Gender and Age, n (%) | ||||
Female | 141 (45.5) | 82 (44.1) | 24 (41.4) | 35 (53) |
Age mean (SD) | 58.7 (18.7) | 62 (18.5) | 50 (17.54) | 56 (17.81) |
Comorbidities, n (%) | ||||
Smoking | 89 (28.7) | 64 (34.4) | 13 (22.4) | 12 (18.2) |
Alcoholism | 37 (11.9) | 25 (13.4) | 8 (13.8) | 4 (6.1) |
COPD | 44 (14.2) | 31 (16.7) | 4 (6.9) | 9 (13.6) |
Diabetes | 50 (16.1) | 31 (16.7) | 8 (13.8) | 11 (16.7) |
Hypertension | 131 (42.3) | 84 (45.2) | 18 (31) | 29 (43.9) |
Heart failure | 40 (12.9) | 33 (17.7) | 3 (5.2) | 4 (6.1) |
Chronic renal disease | 36 (11.6) | 27 (14.5) | 4 (6.9) | 5 (7.6) |
Liver disease | 17 (5.5) | 10 (5.4) | 2 (3.4) | 5 (7.6) |
Obesity | 16 (5.2) | 8 (4.3) | 5 (8.6) | 3 (4.5) |
HIV | 17 (5.5) | 12 (6.5) | 3 (5.2) | 2 (3) |
Coronary artery disease | 26 (8.4) | 20 (10.8) | 1 (1.7) | 5 (7.6) |
Hospital admission in the prior month | 47 (15.2) | 38 (20.4) | 0 (0) | 9 (13.6) |
Previous use of antibiotics | 41 (13.2) | 33 (17.7) | 2 (3.4) | 6 (9.1) |
Dislipidemia | 27 (8.7) | 23 (12.4) | 1 (1.7) | 3 (4.5) |
Atrial fibrillation | 20 (6.5) | 16 (8.6) | 3 (5.2) | 1 (1.5) |
Autoimmune disease | 38 (12.3) | 24 (12.9) | 7 (12.1) | 7 (10.6) |
Cancer | 37 (11.9) | 25 (13.4) | 5 (8.6) | 7 (10.6) |
Epilepsy | 5 (1.6) | 3 (1.6) | 1 (1.7) | 1 (1.5) |
Chronic medications, n (%) | ||||
Antihypertensive drugs | 131 (42.3) | 90 (48.4) | 16 (27.6) | 25 (37.9) |
Oral antidiabetic drugs | 24 (7.7) | 17 (9.1) | 3 (5.2) | 4 (6.1) |
Insulins | 17 (5.5) | 11 (5.9) | 3 (5.2) | 3 (4.5) |
Opioids | 6 (1.9) | 6 (3.2) | 0 (0) | 0 (0) |
PPI | 62 (20) | 45 (24.2) | 4 (6.9) | 13 (19.7) |
Inhaled drug therapy | 25 (8.1) | 17 (9.1) | 1 (1.7) | 7 (10.6) |
Anticoagulant therapy | 11 (3.5) | 10 (5.4) | 0 (0) | 1 (1.5) |
Statins | 44 (14.2) | 37 (19.9) | 2 (3.4) | 5 (7.6) |
NSAID | 16 (5.2) | 9 (4.8) | 2 (3.4) | 5 (7.6) |
Corticosteroid therapy | 32 (10.3) | 23 (12.4) | 3 (5.2) | 6 (9.1) |
Antiepileptic drugs | 6 (1.9) | 3 (1.6) | 2 (3.4) | 1 (1.5) |
Vaccination | ||||
PPV23 | 2 (0.6) | 2 (1.1) | 0 (0) | 0 (0) |
PCV13 | 4 (1.3) | 3 (1.6) | 0 (0) | 1 (1.5) |
Influenza vaccine | 4 (1.3) | 3 (1.6) | 0 (0) | 1 (1.5) |