From: Invasive pneumococcal disease burden in hospitalized adults in Bogota, Colombia
Primary and Secondary Outcomes | All patients (n = 310) | Pneumonia (n = 186) | Meningitis (n = 58) | Others (n = 66) | P value |
---|---|---|---|---|---|
Overall mortality, n (%) | 94 (30.3) | 58 (31.1) | 16 (27.6) | 20 (30.3) | 0.873 |
Mortality in the ICU, n (%) | 64 (20.6) | 38 (20.4) | 10 (17.2) | 16 (24.2) | 0.626 |
Need for invasive mechanical ventilation, n (%) | 141 (45.5) | 81 (43.5) | 36 (62.1) | 24 (36.4) | 0.012 |
Need for non-invasive mechanical ventilation, n (%) | 16 (5.1) | 14 (7.5) | 1 (1.7) | 1 (1.5) | 0.131 |
ICU Admission, n (%) | 163 (52.6) | 97 (52.2) | 37 (63.8) | 29 (43.9) | 0.086 |
Length of ICU stay, median (IQR) | 2 (0–7) | 1.5 (0–8) | 3 (0–8) | 1.5 (0–4.75) | 0.598 |
Length of hospital stay, median (IQR) | 12 (4–21) | 10 (4–21) | 15 (3.75–25) | 9 (3–22.25) | 0.061 |
Time to clinical stability, median (IQR) | 3 (0–10) | 3 (0–10) | 4 (0–10) | 3.5 (0–7) | 0.903 |
Duration of antibiotic treatment, median (IQR) | 10 (3–14) | 10 (3–14) | 14 (4–18) | 7.5 (2–14) | 0.029 |