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Table 4 False negative of mNGS (nā€‰=ā€‰9)

From: Application of mNGS to describe the clinical and microbial characteristics of severe burn a tanker explosion at a tertiary medical center: a retrospective study patients following

Case No

Patient No

Culture

mNGS

Reason

Case 1ā€“3

Case 1

MRSA

Negative

ā€œWeakā€ positive

Case 2ā€“2

Case 2

CRKP

Negative

Severe inflammatory reaction

Case 2ā€“14

Case 2

CRKP

Negative

Severe inflammatory reaction

Case 3ā€“3

Case 3

Candida glabrata

Negative

Difficult to disrupt cellwall

Case 4ā€“3

Case 4

MRSA

Negative

ā€œWeakā€ positive

Case 5ā€“5

Case 5

Fusarium

Negative

Severe inflammatory reaction

Case 8ā€“2

Case 8

Stenotrophomonas maltophilia Enterococcus faecails

Negative

Culture contaminated

Case 12ā€“2

Case 12

CRKP

Negative

Severe inflammatory reaction

Case 12ā€“5

Case 12

CRAB

Negative

ā€œWeakā€ positive

  1. MRSA methicillin-resistant Staphylococcus aureus, CRKP carbapenem-resistant Klebsiella pnermoniae, CRAB carbapenem-resistant Acinetobacter baumannii