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Table 30 Use of macrolides and relationship to mortality (Multivariate analysis adjusted according to clinical variables)

From: Inadequate use of antibiotics in the covid-19 era: effectiveness of antibiotic therapy

 

Odds ratio (95% CI)

p value

Use of macrolides

0.64 (0.56–0.73)

 < 0.001

Age

1.08 (1.07–1.09)

 < 0.001

Smoking status

 Never

–

1 (ref.)

 Former

1.38 (1.19–1.59)

 < 0.001

 Current

1.62 (1.21–2.18)

0.001

Fever

 No (< 37 °C)

–

1 (ref.)

 Low-grade fever (37–37.9 °C)

0.97 (0.79–1.18)

0.76

 Fever (> 38 °C)

0.87 (0.73–1.04)

0.12

 Shortness of breath

1.31 (1.14–1.51)

< 0.001

 Oxygen saturation > 90%

0.45 (0.39–0.51)

< 0.001

 Tachypnea

1.95 (1.70–2.24)

< 0.001

 C-reactive protein (mg/L)

1.01 (1.00–1.01)

< 0.001

 Procalcitonin (ng/mL) > 0.15

4.83 (3.86–6.04)

< 0.001

 Use of systemic corticosteroids

1.60 (1.39–1.84)

< 0.001

 Use of tocilizumab

1.89 (1.49–2.39)

< 0.001