Fig. 2

Random effects meta-analysis on the association between convalescent plasma treatment compared to placebo or no treatment and all-cause mortality in patients with COVID-19, stratified by publication status. CI confidence interval, RR risk ratio. NCT04403477 compares two different volumes of plasma a 400 mL and b 200 mL versus standard of care. To avoid double counting the control arm, the number of patients and number of events were split equally between the two comparisons