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Table 4 Concomitant use with other nephrotoxic medications

From: The impact of early target attainment of vancomycin in critically ill patients with confirmed Gram-positive infection: A retrospective cohort study

Nephrotoxic Medication (s)

Early

Late

P-value

Flucloxacillin IV, n (%)

1 (1.3)

2 (2.6)

0.5754**

Amikacin IV, n (%)

7 (9.2)

5 (6.5)

0.5320^^

Gentamicin IV, n (%)

12 (15.6)

18 (21.7)

0.3231^^

Colistin IV, n (%)

9 (11.8)

10 (12.8)

0.8536^^

Piperacillin/tazobactam IV, n (%)

63 (63.6)

68 (66.0)

0.7229^^

Sulfamethoxazole/trimethoprim IV, n (%)

3 (4.0)

9 (11.1)

0.0958^^

Furosemide IV, n (%)

61 (59.8)

52 (55.3)

0.5255^^

IV Contrast, n (%)

35 (33.7)

40 (38.5)

0.4703^^

  1. ^^Chi-square test is used to calculate the P-value
  2. **Fisher Exact test is used to calculate the P-value