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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: HIV-1 Tat amino acid residues that influence Tat-TAR binding affinity: a scoping review

Fig. 2

Multiple sequence alignment of various HIV-1 Tat subtypes. From top to bottom; Tat subtype H (isolate 90CF056), subtype D (isolate ELI), subtype G (isolate SE6165), subtype B (isolate MN), subtype K (isolate 96CM-MP535), subtype A (isolate U455), subtype J (isolate SE9280) and subtype C (isolate 92BR025). Tat protein is encoded by two exons, exon one spans the region of amino acids 1–72 and exon two spans the region of 73–101. The Tat protein is made up of six function regions including the proline-rich region (1–21), the cysteine-rich region (22–37), the core region (38–48), the basic, arginine-rich domain (49–59), the glutamine-rich domain (60–72) and the RGD domain (73–101). The black arrows indicate the two exons

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