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Bacterial and fungal diseases

This section aims to publish studies looking at all aspects of the prevention, diagnosis and management of bacterial and fungal diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology. This section includes studies relating to antibiotic resistance and healthcare-associated infections.

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  1. The study aimed to assess whether gastrointestinal (GI) symptoms at admission are associated with increased short-term mortality in patients with invasive pneumococcal disease (IPD).

    Authors: Hans Kristian Floeystad, Jacob Dag Berild, Bjoern Jardar Brandsaeter, Didrik Frimann Vestrheim, Dag Berild and Are Martin Holm

    Citation: BMC Infectious Diseases 2020 20:479

    Content type: Research article

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  2. The probability of hospitalization in patients suffering from community-acquired pneumonia (CAP) with an underlying comorbidity, such as a cardiac pathology, is 73-fold higher than that in CAP patients without...

    Authors: Loreto Arias-Fernández, Ruth Gil-Prieto and Ángel Gil-de-Miguel

    Citation: BMC Infectious Diseases 2020 20:477

    Content type: Research article

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  3. Blood culture-negative endocarditis (BCNE) is diagnosed in 2–7% of patients with infective endocarditis (IE) and recent antibiotic use is a known risk factor. Altered mental status may be a presenting symptom....

    Authors: Hossein Sheibani, Mohammad Salari, Elham Azmoodeh, Amirhessam Kheirieh and Sara Chaghazardi

    Citation: BMC Infectious Diseases 2020 20:476

    Content type: Case report

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  4. Carbapenem-resistant hypervirulent Klebsiella pneumoniae strains have recently come into existence worldwide; however, researchers in northeast China are not aware of their clinical features and molecular charact...

    Authors: Shanshan Su, Jisheng Zhang, Yongxin Zhao, Lan Yu, Yong Wang, Yuchao Wang, Mingjia Bao, Yu Fu, Chunjiang Li and Xiaoli Zhang

    Citation: BMC Infectious Diseases 2020 20:472

    Content type: Research article

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  5. Urinary tract infection (UTI) caused by various pathogenic microorganisms is ubiquitous in the parts of the urinary system such as kidney, ureter, bladder, and urethra. Currently, clinical detection of UTI is ...

    Authors: Manshi Li, Fuhuo Yang, Yihan Lu and Weifeng Huang

    Citation: BMC Infectious Diseases 2020 20:467

    Content type: Case report

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  6. Anaplasmosis is an emerging acute febrile disease that is caused by a bite of an Anaplasma phagocytophilum–infected hard tick. As for healthy patients, reports on asymptomatic anaplasmosis resulting from such tic...

    Authors: Jiyeon Yoo, Jong-Hoon Chung, Choon-Mee Kim, Na Ra Yun and Dong-Min Kim

    Citation: BMC Infectious Diseases 2020 20:458

    Content type: Case report

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  7. Uropathogenic E. coli is the leading cause of Urinary tract infections (UTIs), contributing to 80–90% of all community-acquired and 30–50% of all hospital-acquired UTIs. Biofilm forming Uropathogenic E. coli are ...

    Authors: Paul Katongole, Fatuma Nalubega, Najjuka Christine Florence, Benon Asiimwe and Irene Andia

    Citation: BMC Infectious Diseases 2020 20:453

    Content type: Research article

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  8. PCRctic is an innovative assay based on 16S rDNA PCR technology that has been designed to detect a single intact bacterium in a specimen of cerebro-spinal fluid (CSF). The assay’s potential for accurate, fast ...

    Authors: Arthur Abelian, Thomas Mund, Martin D. Curran, Stuart A. Savill, Nipa Mitra, Carol Charan, Amanda L. Ogilvy-Stuart, Hugh R. B. Pelham and Paul H. Dear

    Citation: BMC Infectious Diseases 2020 20:441

    Content type: Research article

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  9. Infection with the Cryptococcus neoformans yeast fungus is largely restricted to patients with HIV, sarcoidosis or immunosuppressive therapies. In sarcoidosis, there is intense local immune response in granuloma ...

    Authors: Johannes H. van der Stoep, Eva Sigstad and Anders Bredberg

    Citation: BMC Infectious Diseases 2020 20:440

    Content type: Case report

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  10. Candida sp. osteoarticular infection is rare and most often due to hematogenous seeding during an episode of candidemia in immunocompromised patients. However, the diagnosis can be delayed in patients with subtle...

    Authors: Kwang Yun Song, Chulmin Park, Ji-Hyun Byun, Hye-Sun Chun, Jung-Hyun Choi, Eun Hee Han, Seung Ok Lee, Yeonjeong Jeong, Youn Jeong Kim and Si-Hyun Kim

    Citation: BMC Infectious Diseases 2020 20:438

    Content type: Case report

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  11. Thyroid gland infections are rare. Their incidence is estimated to be less than 1% in immunocompromised hosts. Most common pathogens isolated are Gram positive aerobic cocci. Infections with Gram negative facu...

    Authors: Maha K. AlYousef, Ahmed A. Al-Sayed, Ayham Al Afif, Uthman Alamoudi, Jaclyn M. LeBlanc and Robin LeBlanc

    Citation: BMC Infectious Diseases 2020 20:436

    Content type: Case report

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  12. Recently, continuous administration of piperacillin-tazobactam has been proposed as a valuable alternative to traditional intermittent administration especially in critically ill patients. However, antibiotic ...

    Authors: Sarah Fawaz, Stephen Barton and Shereen Nabhani-Gebara

    Citation: BMC Infectious Diseases 2020 20:430

    Content type: Research article

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  13. Streptococcus pneumoniae infections can lead to severe morbidity and mortality, especially in patients with invasive pneumococcal disease (IPD). This study evaluated factors associated with pneumococcal disease, ...

    Authors: Tyson Chan, Min Zhi Tay, Win Mar Kyaw, Angela Chow and Hanley J. Ho

    Citation: BMC Infectious Diseases 2020 20:423

    Content type: Research article

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  14. In Kenya, typhoid fever and invasive non-typhoidal salmonellosis present a huge burden of disease, especially in poor-resource settings where clean water supply and sanitation conditions are inadequate. The ep...

    Authors: Cecilia Mbae, Moses Mwangi, Naomi Gitau, Tabitha Irungu, Fidelis Muendo, Zilla Wakio, Ruth Wambui, Susan Kavai, Robert Onsare, Celestine Wairimu, Ronald Ngetich, Frida Njeru, Sandra Van Puyvelde, John Clemens, Gordon Dougan and Samuel Kariuki

    Citation: BMC Infectious Diseases 2020 20:422

    Content type: Research article

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  15. The number of human Q fever cases in South Korea has been rapidly increasing since 2015. We report the first isolation of Coxiella burnetii in Korea in two patients who initially presented with non-specific febri...

    Authors: Seung Hun Lee, Jae Hoon Lee, Sungdo Park, Hae Kyung Lee, Seon Do Hwang, Hye Won Jeong, Jung Yeon Heo and Yeong Seon Lee

    Citation: BMC Infectious Diseases 2020 20:421

    Content type: Case report

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  16. Mycoplasma pneumoniae (M. pneumoniae) is an important pathogen of community-acquired pneumonia (CAP) in children. The coinfection rate of M. pneumoniae pneumonia (MPP) can reach 52% in some areas, but the effects...

    Authors: Jiaojiao Gao, Lili Xu, Baoping Xu, Zhengde Xie and Kunling Shen

    Citation: BMC Infectious Diseases 2020 20:420

    Content type: Research article

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  17. Most serious complications of infective endocarditis (IE) appear in the so-called “critical phase” of the disease, which represents the first days after diagnosis. The majority of patients overcoming the acute...

    Authors: Carmen Olmos, Isidre Vilacosta, Javier López, Carmen Sáez, Manuel Anguita, Pablo Elpidio García-Granja, Cristina Sarriá, Jacobo Silva, Belén Álvarez-Álvarez, María Amparo Martínez-Monzonis, Juan Carlos Castillo, José Seijas, Amanda López-Picado, Vicente Peral, Luis Maroto and J. Alberto San Román

    Citation: BMC Infectious Diseases 2020 20:417

    Content type: Study protocol

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  18. Klebsiella pneumoniae (KP) is the primary pathogen associated with pyogenic liver abscesses (PLAs). Moreover, there has been an increase in the proportion of extended-spectrum beta-lactamase (ESBL)-producing KP. ...

    Authors: Yue Ren, Hairui Wang, Zhihui Chang and Zhaoyu Liu

    Citation: BMC Infectious Diseases 2020 20:416

    Content type: Research article

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  19. Carbapenem is frequently used when gram negative bacilli (GNB) bacteremia is detected especially in neutropenic patients. Consequently, appropriate treatment could be delayed in GNB bacteremia cases involving ...

    Authors: Dong Hoon Shin, Dong-Yeop Shin, Chang Kyung Kang, Suhyeon Park, Jieun Park, Kang Il Jun, Taek Soo Kim, Youngil Koh, Jun Shik Hong, Pyoeng Gyun Choe, Wan Beom Park, Nam-Joong Kim, Sung-soo Yoon, Inho Kim and Myoung-don Oh

    Citation: BMC Infectious Diseases 2020 20:404

    Content type: Research article

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  20. Pneumocystis carinii pneumonia (PCP) prophylaxis is recommended after hematopoietic stem cell transplantation (HSCT). In patients who are unable to take first-line prophylaxis, trimethoprim/sulfamethoxazole, aero...

    Authors: Wedad B. Awad, Alaa Asaad, Nardin Al-Yasein and Rula Najjar

    Citation: BMC Infectious Diseases 2020 20:400

    Content type: Research article

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  21. Disseminated cryptococcosis is a well-characterized complication in immunocompromised patients with cryptococcal pneumonia or meningitis; however, isolated cryptococcal osteomyelitis is a rare entity that occu...

    Authors: Takashi Matsuki, Shunsuke Miyamoto and Taku Yamashita

    Citation: BMC Infectious Diseases 2020 20:399

    Content type: Case report

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  22. Primary aim of this study was to compare cognitive performance of patients with chronic Q fever or Q fever fatigue syndrome (QFS) to matched controls from the general population, while taking performance valid...

    Authors: Daphne F. M. Reukers, Justine Aaronson, Joris A. F. van Loenhout, Birte Meyering, Koos van der Velden, Jeannine L. A. Hautvast, Cornelia H. M. van Jaarsveld and Roy P. C. Kessels

    Citation: BMC Infectious Diseases 2020 20:397

    Content type: Research article

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  23. Delayed antifungal therapy for candidemia leads to increased mortality. Differentiating bacterial infection from candidemia in systemic inflammatory response syndrome (SIRS) patients is complex and difficult. ...

    Authors: So Yeon Park, Jin Seo Lee, Jihyu Oh and Ji-Young Park

    Citation: BMC Infectious Diseases 2020 20:396

    Content type: Research article

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  24. Talaromyces marneffei is a highly pathogenic fungus that can cause life-threatening fatal systemic mycosis. Disseminated Talaromycosis marneffei affects multiple organs, including the lungs, skin, and reticuloend...

    Authors: Mianluan Pan, Ye Qiu, Wen Zeng, Shudan Tang, Xuan Wei and Jianquan Zhang

    Citation: BMC Infectious Diseases 2020 20:394

    Content type: Case report

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  25. The first yaws eradication campaign reduced the prevalence of yaws by 95%. In recent years, however, yaws has reemerged and is currently subject to a second, ongoing eradication campaign. Yet, the epidemiologi...

    Authors: Clara K. C. Lubinza, Simone Lueert, Luisa K. Hallmaier-Wacker, Esther Ngadaya, Idrissa S. Chuma, Rudovick R. Kazwala, Sayoki G. M. Mfinanga, Klaus Failing, Christian Roos and Sascha Knauf

    Citation: BMC Infectious Diseases 2020 20:392

    Content type: Research article

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  26. Intracranial infections with Corynebacterium striatum (C. striatum) have been described sporadically in the literature over the last two decades. However, C. striatum meningitis combined with multiple abscesses h...

    Authors: Ming-Jie Zhang, Xiao-Jie Cao, Jin Fan, Ze-Gang Yin and Ke Yu

    Citation: BMC Infectious Diseases 2020 20:389

    Content type: Case report

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  27. A particular ability of the Staphylococcus aureus clonal complex 398 (CC398) to cause bone and joint infections (BJI) remains questionable, since some studies have described high prevalence of MSSA CC398 in prost...

    Authors: Kevin Bouiller, Didier Hocquet, Marlene Sauget, Xavier Bertrand and Catherine Chirouze

    Citation: BMC Infectious Diseases 2020 20:384

    Content type: Research article

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  28. Clinicians may be less inclined to consider a diagnosis of cryptococcal meningitis in people without HIV infection or transplant-related immunosuppression. This may lead to a delay in diagnosis particularly if...

    Authors: Christopher Polk, Jacqueline Meredith, Alyssa Kuprenas and Michael Leonard

    Citation: BMC Infectious Diseases 2020 20:381

    Content type: Case report

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  29. Brain abscesses are the rare and most severe form of actinomycosis, which usually manifests as abscesses of the occipital or parietal lobe due to direct expansion from an adjacent area, the oral cavity. In the...

    Authors: Ranjit Sah, Gaurav Nepal, Sanjit Sah, Sonam Singla, Priti Upadhyay, Ali A. Rabaan, Kuldeep Dhama, Alfonso J. Rodriguez-Morales and Rabindra Ghimire

    Citation: BMC Infectious Diseases 2020 20:378

    Content type: Case report

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  30. Candida diddensiae, a yeast found in olive oil, is considered non-pathogenic to humans. Here, we describe the first case of fungemia caused by C. diddensiae in a hospitalized patient with underlying diseases.

    Authors: Seong Eun Kim, Sook In Jung, Kyung-Hwa Park, Yong Jun Choi, Eun Jeong Won and Jong Hee Shin

    Citation: BMC Infectious Diseases 2020 20:377

    Content type: Case report

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  31. Elevated Staphylococcus aureus and oral bacterial concentrations are known to correlate with pneumonia hospitalization in nursing home residents. However, the effects of a professional oral care intervention on t...

    Authors: Tien-Cheng Chiang, Ming-Shyan Huang, Po-Liang Lu, Shun-Te Huang and Ying-Chu Lin

    Citation: BMC Infectious Diseases 2020 20:374

    Content type: Research article

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  32. Brain abscesses, a severe infectious disease of the CNS, are usually caused by a variety of different pathogens, which include Streptococcus intermedius (S. intermedius). Pulmonary arteriovenous fistulas (PAVFs),...

    Authors: Lu-Yao Gao, Guang-Run Xu and Ting-Jun Dai

    Citation: BMC Infectious Diseases 2020 20:370

    Content type: Case report

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  33. Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community acquired pneumonia (CAP). Establishing an early diagnosis of M. pneumoniae pneumonia in patients with acute respiratory distress...

    Authors: Lin Ding, Yu Zhao, Xuyan Li, Rui Wang, Ying Li, Xiao Tang, Bing Sun and Hangyong He

    Citation: BMC Infectious Diseases 2020 20:367

    Content type: Research article

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  34. Kosakonia cowanii, formerly known as Enterobacter cowanii, is a Gram-negative bacillus belonging to the order Enterobacterales. The species is usually recognized as a plant pathogen and has only anecdotally been ...

    Authors: Benjamin Berinson, Eugen Bellon, Martin Christner, Anna Both, Martin Aepfelbacher and Holger Rohde

    Citation: BMC Infectious Diseases 2020 20:366

    Content type: Case report

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  35. Reports of human rickettsial infection in Indonesia are limited. This study sought to characterize the epidemiology of human rickettsioses amongst patients hospitalized with fever at 8 tertiary hospitals in In...

    Authors: Dewi Lokida, Usman Hadi, Chuen-Yen Lau, Herman Kosasih, C. Jason Liang, Musofa Rusli, Pratiwi Sudarmono, Nurhayati Lukman, Kanti Laras, Rizka Humardewayantie Asdie, Dewi Murniati, I Made Susila Utama, Risna Halim Mubin, Muhammad Karyana, Muhammad Hussein Gasem and Bachti Alisjahbana

    Citation: BMC Infectious Diseases 2020 20:364

    Content type: Research article

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  36. Globally, in 2012, about 1.2 million estimated cases were reported with ~ 135,000 deaths annually. In Ethiopia, specifically in our study area, limited information is found on the oropharyngeal carriage, antim...

    Authors: Zelalem Tefera, Feleke Mekonnen, Moges Tiruneh and Teshome Belachew

    Citation: BMC Infectious Diseases 2020 20:358

    Content type: Research article

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  37. We report a case of subdural empyema in a homeless patient caused by Bartonella quintana. B. quintana is a facultative intracellular bacteria for which bacterial growth is fastidious. The molecular biology approa...

    Authors: Cécile Brin, Wladimir Sougakoff, Franck Bielle, Samya Abi Jaoude, Isabelle Bonnet, Elie Haddad, Eric Caumes and Stéphane Jauréguiberry

    Citation: BMC Infectious Diseases 2020 20:357

    Content type: Case report

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  38. Vancomycin-resistant Enterococcus spp. (VRE) have spread all over the world. The present study aims to investigate the species distribution, specimen type and susceptibilities of Enterococcal species collected fr...

    Authors: Wanqing Zhou, Hui Zhou, Yuhan Sun, Shuo Gao, Yan Zhang, Xiaoli Cao, Zhifeng Zhang, Han Shen and Chunni Zhang

    Citation: BMC Infectious Diseases 2020 20:356

    Content type: Research article

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  39. Mediastinitis caused by hematogenous spread of an infection is rare. We report the first known case of community-acquired mediastinitis from hematogenous origin in an immunocompetent adult. This rare invasive ...

    Authors: Josselin Brisset, Thomas Daix, Jérémy Tricard, Bruno Evrard, Philippe Vignon, Olivier Barraud and Bruno François

    Citation: BMC Infectious Diseases 2020 20:354

    Content type: Case report

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  40. The aim of the study was to identify the pathogens, in addition to bordetella pertussis (B. pertussis), which cause pertussis-like syndrome in children and to compare clinical presentation between those with B. p...

    Authors: Wenjing Gu, Kun Wang, Xinxing Zhang, Chuangli Hao, Yanhong Lu, Min Wu, Sainan Chen, Yanyu He, Jun Xu, Xuejun Shao and Yuqing Wang

    Citation: BMC Infectious Diseases 2020 20:353

    Content type: Research article

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  41. Eikenella corrodens and Streptococcus anginosus, which are primary colonization bacteria of the normal flora of the oropharynx, are infrequent bacteria, especially the former. Here, we report a case of lung absce...

    Authors: Leihao Hu, Jietao Lin, Jing Li, Yang Cao and Lizhu Lin

    Citation: BMC Infectious Diseases 2020 20:351

    Content type: Case report

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  42. Purulent pericarditis is an infectious disease, frequently caused by gram-positive bacteria, that is rarely observed in healthy individuals, and is often associated with predisposing conditions.

    Authors: Ilenia Magnani, Alberto Spadotto, Pasquale Paolisso, Alberto Foà, Carlo Savini, Davide Pacini, Carmine Pizzi and Nazzareno Galiè

    Citation: BMC Infectious Diseases 2020 20:342

    Content type: Case report

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  43. The aim of this study was to evaluate the influence of patient body mass index (BMI) and estimated creatinine clearance (CrCl) on serum vancomycin concentrations to define a possible optimal dosage regimen in ...

    Authors: Yuyan Pan, Xiaomei He, Xinyu Yao, Xiaofeng Yang, Fengjiao Wang, Xinyuan Ding and Wenjuan Wang

    Citation: BMC Infectious Diseases 2020 20:341

    Content type: Research article

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