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Table 5 One way sensitivity analysis on the incremental cost effectiveness ratio (ICER) for selected input factors with the highest influence on the model shown for a current usage on malaria chemoprophylaxis of 68.7%

From: Cost-effectiveness analysis of malaria chemoprophylaxis for travellers to West-Africa

Scenario

€/'malaria cases averted'*

Current probability of recourse to malaria chemoprophylaxis

 

   Very low (40%)

dominant

   Low (55%)

dominant

   High (82.4%)

2'302

Probability of contracting malaria without malaria chemoprophylaxis for a two week stay

 

   Extremly low (= 0.4%)

19'899

   Very low (= 0.9%)

5'922

   Low, (= 1.2%)

3'126

   A bit low, -30% (= 1.7%)

548

   High, +30% (= 3.1%)

dominant

Cost of the mefloquine drug

 

   Low, -30% (= € 15.54)

dominant

   High, +30% (= € 28.86)

dominant

Decrease of 'non-malaria chemoprophylaxis-users' due to the 80% reimbursement

 

   Low, -30% (40%)

126

   High, +30% (74%)

dominant

Reimbursement of the more expansive drugs

 

   Doxycycline (€ 30.23)

dominant

   80% reimbursement of all three drugs

4'968

Percentage of reimbursement of the cheapest malaria chemoprophylaxis

 

   Very low (60%)

dominant

   Low (70%)

dominant

   High (90%)

dominant

   Very High (100%)

dominant

  1. *the incremental cost effectiveness ratio (ICER) per averted malaria case