Predicting results of mycobacterial culture on sputum smear reversion after anti-tuberculous treatment: a case control study

Table 2 Laboratory and radiographic findings in patients with smear reversion.

	Mtb group (n = 22)	Non-Mtb group (n = 52)	pvalue
Mycobacterial load at smear reversion			0.007
High	3 (14%)	1 (2%)
Medium	8 (36%)	9 (17%)
*Resistance of pre-treatment Mtb isolate
Any TB drug resistance	11 (50%)	9 (17%)	0.004
Multidrug resistance	5 (23%)	1 (2%)	0.009
Finding of chest film
Bilateral involvement at initial	16 (73%)	33 (63%)	0.441
Cavitary lesion at initial	7 (32%)	12 (23%)	0.431
Not improved at smear reversion	19 (86%)	27 (52%)	0.005
Blood tests at reversion
Leukocyte (>11000 or <4000/μL)	6 (27%)	11 (21%)	0.555
Hemoglobin (< 12 g/dL)	13 (63%)	19 (42%)	0.055
Albumin (< 3.5 g/dL)	4 (36%)	7 (50%)	0.495
Total Bilirubin (> 1.2 mg/dL)	2 (11%)	6 (16%)	0.614
Creatinine (> 1.5 mg/dL)	3 (17%)	4 (9%)	0.358

Abbreviation: Mtb, Mycobacterium tuberculosis; TB, tuberculosis
Data are no. (%) or mean [no. of tested patients], unless otherwise indicated.
*The details of resistance of pre-treatment isolate were described in additional file 1: Table S2.

ISSN: 1471-2334