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Table 1 Susceptibility pattern of nosocomial infection agents obtained at local and central laboratories.

From: Comparative in vitro activity of Meropenem, Imipenem and Piperacillin/tazobactam against 1071 clinical isolates using 2 different methods: a French multicentre study

Drugs

% Susceptibility (Number tested)

 

Locally determined

Centralized

 

Routine

Etest

Agar DM

Escherichia coli

Meropenem

100 (92)

100 (139)

100 (139)

Imipenem

100 (139)

100 (139)

100 (139)

Piperacillin/tazobactam*

82 (139)

89 (139)

90 (139)

Enterobacteriaceae (other than E coli)

Meropenem

100 (86)

99 (139)

99 (139)

Imipenem

99 (139)

97 (139)

97 (139)

Piperacillin/tazobactam*

78 (139)

86 (139)

99 (139)

Pseudomonas aeruginosa

Meropenem

87 (87)

91 (129)

95 (129)

Imipenem

78 (137)

70 (129)

84 (129)

Piperacillin/tazobactam*

88 (136)

89 (129)

90 (129)

Acinetobacter

Meropenem

88 (50)

87 (86)

95 (79)

Imipenem

94 (84)

94 (86)

97 (79)

Piperacillin/tazobactam*

79 (82)

80 (86)

100* (79)

Other non fermentative bacteria

Meropenem

73 (33)

89 (33)

88 (33)

Imipenem

85 (41)

87 (33)

88 (33)

Piperacillin/tazobactam*

90 (41)

97 (33)

90 (33)

Staphylococcus aureus (susceptible to methicillin)

Meropenem

-

100 (145)

100 (145)

Imipenem

-

100 (145)

100 (145)

Piperacillin/tazobactam*

-

100 (145)

100 (145)

Coagulase negative staphylococci (susceptible to methicillin)

Meropenem

-

100 (129)

100 (129)

Imipenem

-

100 (129)

100 (129)

Piperacillin/tazobactam*

-

100 (129)

100 (129)

Streptococcus pneumoniae

Meropenem

-

100 (136)

100 (136)

Imipenem

-

100 (136)

100 (136)

Piperacillin/tazobactam*

-

100 (136)

100 (136)

  1. *Tazobactam: 4 mg/L