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Table 4 Multivariate analysis of factors associated with mortality among cases of hospital-associated and community-acquired Staphylococcus aureus bacteraemia in Denmark from 1995-2008

From: Stable incidence and continued improvement in short term mortality of Staphylococcus aureus bacteraemia between 1995 and 2008

 

Hospital-associated SAB

Community-acquired SAB

 

30-d mortality (%)

Adjusted MRR (95% CI)

30-d mortality (%)

Adjusted MRR (95% CI)

Overall

2368/9412 (25.2%)

 

1439/5074 (28.4%)

 

Age, years

    

 1 >

19/337 (5.6%)

0.45 (0.28-0.73)

1/58 (1.7%)

0.13 (0.02-0.93)

 1-15

9/232 (3.9%)

0.27 (0.14-0.53)

1/235 (0.4%)

0.03 (0.04-0.23)

 16-35

32/535 (6.0%)

0.39 (0.27-0.56)

15/405 (3.7%)

0.25 (0.14-0.42)

 36-55

282/1733 (16.3%)

1.0

152/938 (16.2%)

1.0

 56-75

983/3982 (24.7%)

1.7 (1.5-1.9)

483/1734 (27.9%)

1.8 (1.5-2.2)

 > 75

1043/2593 (40.2%)

3.2 (2.8-3.7)

787/1704 (46.2%)

3.6 (3.0-4.4)

Sex

    

 Female

988/3755 (26.3%)

1.0

616/1927 (32.0%)

1.0

 Male

1380/5657 (24.4%)

0.90 (0.83-0.98)

823/3147 (26.2%)

0.82 (0.74-0.92)

CCI score

    

 0

527/2822 (18.7%)

1.0

435/2293 (19.0%)

1.0

 1-2

1049/3868 (27.1%)

1.3 (1.1-1.4)

606/1801 (33.6%)

1.3 (1.1-1.5)

 > 2

792/2722 (29.1%)

1.4 (1.2-1.6)

398/980 (40.6%)

1.6 (1.4-1.9)

Alcohol-related disorders

    

 No

2113/8585 (24.6%)

1.0

1251/4532 (27.6%)

1.0

 Yes

255/827 (30.8%)

1.7(1.5-2.0)

188/542 (34.7%)

1.9(1.6-2.2)

Year

    

 1995-1997

526/1893 (27.8%)

1.0

262/989 (26.5%)

1.0

 1998-2000

502/1992 (25.2%)

0.83 (0.74-0.94)

365/1261 (28.9%)

1.00 (0.85-1.17)

 2001-2003

512/2010 (25.5%)

0.79 (0.70-0.89)

257/893 (28.8%)

0.89 (0.75-1.06)

 2004-2006

535/2171 (24.6%)

0.74 (0.66-0.84)

355/1155 (30.7%)

0.90 (0.76-1.05)

 2007-2008

293/1346 (21.8%)

0.65 (0.56-0.75)

200/776 (25.8%)

0.74 (0.61-0.89)

  1. SAB: Staphylococcus aureus bacteraemia; MRR: Mortality rate ratio; CI: confidence interval, CCI: Charlson comorbidity index.