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Table 3 Risk of low-grade squamous intraepithelial neoplasia (LSIL) diagnosis at each visit given vaginal pH measurement, stratified by age at visit

From: A large, population-based study of age-related associations between vaginal pH and human papillomavirus infection

Vaginal pH Level

N

Percent with LSIL

Odds of LSIL Cytologya (95% CI)

p-value

All Womenb

    

4.0-4.5

19,272

2.4

ref

< 0.01

5.0-5.5

9,059

2.5

1.3 (1.1-1.6)

 

Age at Visit

    

< 25 years

    

4.0-4.5

1,536

4.0

ref

0.12

5.0-5.5

475

5.7

1.5 (0.9-2.3)

 

25-34 years

    

4.0-4.5

6,178

2.9

ref

0.02

5.0-5.5

1,721

4.0

1.4 (1.0-1.9)

 

35-44 years

    

4.0-4.5

6,074

2.3

ref

0.30

5.0-5.5

1,568

2.8

1.2 (0.9-1.7)

 

45-54 years

    

4.0-4.5

3,216

1.9

ref

0.33

5.0-5.5

1,776

2.3

1.2 (0.8-1.8)

 

55-64 years

    

4.0-4.5

1,308

1.3

ref

0.82

5.0-5.5

1,653

1.4

1.1 (0.6-1.9)

 

65+ years

    

4.0-4.5

960

0.5

ref

0.04

5.0-5.5

1,866

1.4

2.7 (1.0-7.0)

 
  1. a Generalized estimating equation models with an independent correlation structure were used to estimate the odds of testing positive LSIL given dichotomous pH measurements at each visit
  2. b Adjusted for age at visit