Table 3 Factors associated with HIV positive persons developing (single measurement) eGFR of <60 ml/min/1.73 m 2 who had baseline eGFR > 90 /ml/min1.73/m 2
Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | ||
Centre | Pune | 4.87 | 2.28, 10.38 | <0.0001 | 7.65 | 3.36, 17.41 | <.0001 |
RF | 1.00 | - | 1.00 | - | |||
Age | Per 10 years older | 1.85 | 1.43, 2.40 | <.00001 | 2.21 | 1.61, 3.05 | <.0001 |
Gender | Female | 1.63 | 0.89, 2.99 | 0.12 | 1.72 | 0.90, 3.29 | 0.10 |
Male | 1.00 | - | 1.00 | - | |||
Receiving PI | Yes | 1.01 | 0.57, 1.79 | 0.97 | 2.40 | 1.21, 4.76 | 0.01 |
No | 1.00 | - | 1.00 | - | |||
CD4 count | Per 100 cells | 1.01 | 0.90, 1.13 | 0.89 | 1.04 | 0.89, 1.20 | 0.65 |
Time since diagnosis | Per year longer | 0.98 | 0.92, 1.04 | 0.46 | 1.00 | 0.92, 1.07 | 0.92 |
CD4 nadir | Per 100 cells | 0.94 | 0.78, 1.14 | 0.55 | 0.99 | 0.79, 1.23 | 0.91 |
Ever received a PI before TDF | Yes | 0.76 | 0.32, 1.78 | 0.52 | 0.77 | 0.28, 2.15 | 0.62 |
No | 1.00 | - | 1.00 | - | |||