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Figure 2 | BMC Infectious Diseases

Figure 2

From: Prevention of Clostridium difficilespore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam

Figure 2

Vegetative cells and spores growing on agar after 48 h of growth in liquid TY broth containing 0.5x MIC of TIGE (orange dots) or VAN (blue dots). No ATB = control without antibiotic (grey dots). Dots represent the Log10 counts from 3 independent experiments (each done in duplicate). The dashed line indicates the limit of detection in our assay, which was 40 CFU/mL. When the spore count was below the limit of detection, the value was arbitrarily set at 40 CFU/mL. The mean values of % spores are indicated above each corresponding group for reference. The mean spore counts in the presence of antibiotics were compared with the control without antibiotics by one-way ANOVA. The boxes below each graph represent the mean % spores determined after 48 h and 96 h using the microscopic method. The values were compared by ANOVA. Statistical significance: * = p < 0.05; ** = p < 0.01; *** = p < 0.001; **** = p < 0.0001.

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