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Table 2 Factors related with occurrence of tuberculosis in household contacts

From: Tuberculosis burden in China: a high prevalence of pulmonary tuberculosis in household contacts with and without symptoms

 

Number of IC*

Number of contacts

Cases in contacts

Prevalence (1/100,000)

OR

AOR†

Index patients

      

Age

      

  0-14

7

12

1

8333

1.00

1.00

  15-64

1224

2568

69

2687

0.31 (0.03, 3.48)

0.40 (0.03, 1.50)

  65-

334

773

22

2846

0.33 (0.03, 3.87)

0.46 (0.04, 5.40)

Sex

      

  Woman

434

967

37

3826

1.00

1.00

  Man

1141

2388

55

2303

0.59 (0.37, 0.94)‡

0.60 (0.36, 0.99)‡

Cavitary disease

      

  No

1153

2471

66

2671

1.00

1.00

  Yes

414

868

26

2995

1.12 (0.67, 1.86)

1.22 (0.72, 2.07)

Treatment history

      

  New

1427

3089

80

2590

1.00

1.00

  Re-treatment

144

258

12

4651

1.75 (0.80, 3.38)

1.65 (0.45, 3.23)

Treatment delay

      

  No

304

698

11

1576

1.00

1.00

  Yes

1217

2657

81

3049

1.91 (0.98, 3.73)

1.70 (0.85, 3.71)

Household contacts

      

Age

      

  0-14

 

359

4

1114

1.00

1.00

  15-64

 

2649

70

2643

2.28 (0.83, 6.28)

2.30 (0.84, 6.30)

  65-

 

342

18

5263

4.77 (1.59, 14.37)‡

4.96 (1.85, 14.89)‡

Sex

      

  Woman

 

1795

42

2340

1.00

1.00

  Man

 

1560

50

3205

1.40 (0.91, 2.14)‡

1.52 (1.18, 2.32)‡

Symptoms

      

  No

 

3101

46

1483

1.00

1.00

  Yes

 

254

46

18110

14.10 (8.91,22.31)‡

13.94 (8.61,12.59)‡

Index patients and household contacts

Relationship

      

  Couple

 

949

39

4110

1.00

1.00

  Parent

 

654

20

3058

0.73 (0.41, 1.29)

0.55 (0.20, 1.49)

  Children

 

939

18

1917

0.44 (0.24, 0.79)‡

0.35 (0.12, 0.92)‡

  Sister/brother

 

242

10

4132

0.86 (0.39, 1.89)

0.72 (0.23, 2.28)

  Other

 

544

5

921

0.22 (0.08, 0.56)‡

0.40 (0.21, 0.77)‡

Whether living same bedroom

      

  No

 

2368

55

2323

1.00

1.00

  Yes

 

987

37

3749

1.70 (1.09, 2.63)‡

1.35 (0.74, 2.50)

Random effect

      

  Constant

     

3.08 (1.05, 9.09)‡

  1. Remark: * IC is Index Cases. †AOR is adjusted odds ratios. ‡ indicate 95% significant.