From: The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis
Numbers in parenthesis indicate % | TB | Control |
---|---|---|
Age (median; range in years) | 28; 18–52 | 28; 19–48 |
Sex (male) | 9 (60) | 8 (53) |
Ethnicity | Â | Â |
   Black African | 9 (60) | 8 (53) |
   Indian | 4 (26) | 4 (26) |
   Other | 2 (14) | 3 (21) |
X-ray features | Â | Â |
Cavitation | 8 (53) | 0 |
>50% airspace shadowing of total lung field | 7 (47) | 0 |
BAL (mean ± SE) |  |  |
Total leucocytes (× 104/ml) | 31 ± 8 | 12.8 ± 4.2 |
lymphocyte count (× 104/ml) | 15 ± 4 | 2.7 ± 1.4 |
CD4: CD8 ratio | 3.8 ± 1 | 2.55 ± 0.9 |
IFN-γ copy number | 3390 [1525–7498] | 13 [4–113]; p = 0.0005 |
Th1/Th2 ratio | 3.5 [3.1–3.8] | 1.1 [.4–1.8]; p = 0.0007 |