Figure 3
TNF-α protein levels in the plasma 24 hours after PCI. Naive, non-infected control rats, naive rats treated with G-CSF only (20 μg/kg, 12 h before and 12 h after PCI), PCI rats without prophylaxis, PCI rats with antibiotic prophylaxis (coamoxiclav = CoA or ceftriaxone/metronidazole = Cef/met) and PCI rats with antibiotic plus G-CSF prophylaxis were analysed. Cytokine levels were determined by ELISA. ANOVA analysis of variance revealed P < 0.001 for n = 9/group and post hoc tests of with Bonferroni correction obtained a significant increase of the cytokine level in all infected animals compared to control (P < 0.01) and *P < 0.05 versus PCI, **P < 0.01 versus PCI and #P < 0.05 versus coamoxiclav. Data are presented as mean ± SEM.