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Table 3 Comparison of Mycoplasma pneumonia with positive PCR from respiratory samples to patients with positive serology results

From: Mycoplasma pneumoniaepneumonia revisited within the German Competence Network for Community-acquired pneumonia (CAPNETZ)

Variables

PCR positive

n = 148

Only IgM positive

n = 159

p-value1

Only IgA positive

n = 826

p-value2

Only IgG

positive

n = 973

p-value3

Age ≥ 50 years

23.6%

23.3%

.841

67.6%

.000

60.5%

.000

Male gender

45%

38%

.240

58%

.003

54%

.026

Smoker

29%

42%

.017

37%

.037

34%

.243

Initial treatment setting

       

   -outpatient

66%

46%

.000

33%

.000

39%

.000

   -hospitalized

34%

54%

 

67%

 

61%

 

Fever

68%

59%

.081

55%

.003

56%

.004

Confusion

3%

2%

.632

9%

.013

8%

.023

CRB 65 Score

       

0

74%

70%

.499

41%

.000

46%

.000

1–2

22%/4%

29%/1%

 

42%/13%

 

38%/12%

 

3–4

0

1%/0

 

2%/1%

 

3%/1%

 

Mechanical ventilation

0

1 patient

.332

23 patients

.040

20 patients

.078

Died within 30 days

1 patient

(0.7%)

1 patient

(0.6%)

.963

62 patients

(7.5%)

.002

61 patients

(6.3%)

.006

  1. Patients with positive PCR were compared to IgM only (column p-values1) positive patients, to patients with only positive IgA (column p-values2) and patients with positive IgG only (column p-values3), respectively. Forty-six patients were positive in PCR and IgM, 55 patients were positive in PCR and IgA and 69 patients were positive in PCR as well as in IgG.