Phenotypic and functional evaluations of peripheral blood monocytes from chronic-form paracoccidioidomycosis patients before and after treatment

Table 1 Clinical characterization of the patients

Patients	Sex	Age^*	Degree of severity^*	DID (1: ) - Admission^*	Group	Antifungal	Length of treatment (months)^**	Length after treatment (months)^**
P1	M	60	Moderate	16	NTG	-	-	-
P2	M	53	Severe	128	NTG	-	-	-
P3	M	59	Moderate	32	NTG	-	-	-
P4	F	47	Moderate	64	NTG	-	-	-
P5	M	44	Moderate	64	NTG	-	-	-
P6	M	51	Mild	NR	NTG	-	-	-
P7	M	64	Moderate	32	NTG	-	-	-
P8	M	59	Moderate	32	NTG	-	-	-
P9	M	52	Moderate	8	NTG	-	-	-
P10	M	47	Moderate	32	NTG	-	-	-
P11	M	37	Moderate	4	NTG	-	-	-
P12	M	56	Moderate	16	ACG	CMX	25	28
P13	M	39	Severe	64	ACG	CMX	173	37
P14	M	60	Mild	16	ACG	CMX	97	45
P15	M	56	Moderate	16	ACG	CMX	26	3
P16	M	50	Moderate	512	ACG	CMX	53	62
P17	M	42	Moderate	8	ACG	CMX	28	83
P18	M	42	Moderate	NR	ACG	ITC	31	69
P19	M	39	Moderate	2	ACG	ITC	32	27
P20	M	40	Severe	128	ACG	CMX/ITC	33^(CMX)/49^(ITC)	89
P21	M	42	Severe	64	ACG	CMX/ITC	6^(CMX)/131^(ITC)	53
P22	M	51	Severe	128	ACG	CMX/ITC	44^(CMX)/12^(ITC)	60
P23	M	53	Severe	64	ACG	CMX	84	65

DID = double agar gel immunodiffusion test; NR = non-reagent; NTG = non-treated group; ACG = apparent cure group; CMX = cotrimoxazole; ITC = Itraconazole.
*Homogeneity (NTG x ACG):
Age: NTG =52 (37–64); ACG = 46 (39-60); p =0.18 (Mann–Whitney U test).
Degree of severity: NTG = ACG; p =0.31 (Fisher's exact test).
DID admission: NTG =32 (NR-1:128); ACG =32 (NR-1:512); p =0.66 (Mann-Whitney U test).
**Length of treatment (Mean ± SEM): 68 ± 14; Length after treatment (Mean ± SEM): 52 ± 7.

ISSN: 1471-2334