From: Antibiotic use for Vibrio infections: important insights from surveillance data
Na | Crude mortality % (95% CI) | Comparison with Quinolone only p value | |
---|---|---|---|
CDC treatment recommendationb | |||
Quinolone only | 14/84 | 16.7 (10.2-26.1) | - |
Tetracycline + cephalosporin (all generations) | 49/226 | 21.7 (16.8-27.5) | 0.329 |
Tetracycline + 3rd generation cephalosporin | 39/182c | 21.4 (16.1-28.0) | 0.366 |
Other combinations | |||
Quinolone + cephalosporin (all generations) | 24/98 | 24.5 (17.1-33.9) | 0.195 |
Quinolone + tetracycline | 15/95 | 15.8 (9.8-24.4) | 0.874 |
Quinolone + cephalosporin + tetracycline | 15/87 | 17.2 (10.7-26.5) | 0.920 |
Other single antibiotics | |||
Tetracycline alone | 30/145 | 20.7 (14.9-28.0) | 0.456 |
Cephalosporin alone (all generations) | 39/106 | 36.8 (28.2-46.3) | 0.002 |
Penicillin alone | 18/54 | 33.3 (22.2-46.6) | 0.024 |
No antibiotic | 156/305 | 51.1 (45.6-56.7) | <0.001 |