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Table 5 Demographic, clinical and laboratory data of children with a Salmonella Typhimurium or Salmonella Enteritidis infection, Oriental Province, DRC, 2009–2014. Except for age, data represent numbers (%)

From: Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo

 

Salmonella Typhimurium

Salmonella Enteritidis

Bivariate analysis

Characteristics

N

Yes (%)

N

Yes (%)

OR (CI)

p-value

Demographics

      

Median age, months (IQR)

51

18 (12–30)

47

24 (12–48)

1.00 (0.99–1.02)

0.275

Male gender

53

27 (50.9)

52

33 (63.5)

1.66 (0.77–3.56)

0.188

Nutritional data (age <60 months)

      

Low weight-for-age

38

8 (21.1)

30

6 (20.0)

0.93 (0.28–3.07)

0.915

Very low weight-for-age

38

6 (15.8)

30

5 (16.7)

1.06 (0.29–3.90)

0.922

Symptoms at admission

      

Vomiting

40

17 (42.5)

33

16 (48.5)

1.27 (0.50–3.21)

0.609

Diarrhea

40

9 (22.5)

33

12 (36.4)

1.96 (0.70–5.49)

0.196

Cough

40

25 (62.5)

33

15 (45.5)

0.5 (0.19–1.27)

0.147

Dyspnea

40

19 (47.5)

33

16 (48.5)

1.04 (0.41–2.61)

0.933

Lethargy

40

22 (55.0)

33

21 (63.6)

1.43 (0.55–3.67)

0.456

Coma

40

1 (2.5)

33

0 (0.0)

*

1.000b

Seizures

40

7 (17.5)

33

0 (0.0)

*

0.014b

Pallor

40

29 (72.5)

33

28 (84.8)

2.12 (0.65–6.89)

0.210

Splenomegaly

37

7 (18.9)

30

11 (36.7)

2.48 (0.81–7.51)

0.108

Hepatomegaly

37

6 (16.2)

30

7 (23.3)

1.57 (0.46–5.30)

0.466

Antibiotic exposure < 2 week

49

15 (30.6)

44

19 (43.2)

1.72 (0.73–4.03)

0.211

Diagnosis upon admission

      

Malaria

52

23 (44.2)

52

34 (65.4)

2.38 (1.07–5.25)

0.032

Pneumonia

52

9 (17.3)

52

7 (13.5)

0.74 (0.25–2.17)

0.588

Typhoid fever

52

11 (21.2)

52

8 (15.4)

0.67 (0.24–1.85)

0.448

Septicemia

52

5 (9.6)

52

8 (15.4)

1.70 (0.51–5.62)

0.378

Urinary tract infection

52

1 (1.9)

52

4 (7.7)

4.25 (0.45–39.38)

0.203

Gastro-intestinal tract infection

52

3 (5.7)

52

1 (1.9)

0.32 (0.03–3.18)

0.331

Meningitis

52

4 (7.7)

52

4 (7.7)

1.00 (0.23–4.23)

1.000

Other diagnosis

52

6 (11.5)

52

7 (13.5)

1.19 (0.37–3.82)

0.767

Laboratory data

      

Malaria diagnosisa

40

25 (62.5)

33

27 (81.8)

2.7 (0.90–8.04)

0.075

Anemia (Hb < 11 g/dl)

39

38 (97.4)

33

33 (100)

*

1.000b

Severe anemia (Hb < 5 g/dl)

39

10 (25.6)

33

12 (36.4)

1.65 (0.60–4.54)

0.327

Transfusion/Outcome

      

Blood transfusion

40

25 (62.5)

33

24 (70.6)

1.60 (0.58–4.34)

0.356

Died in hospital

40

7 (17.5)

33

3 (9.1)

0.47 (0.11–1.98)

0.306

  1. OR Odd’s’ratio
  2. *Predicts failure perfectly
  3. aMalaria diagnosis as confirmed by either thick blood film microscopy or rapid diagnostic test
  4. bFisher exact test was used to calculate p value (other variables: logistic regression)