Table 3 Comparison of in-hospital mortality rates according to the clinical severity of healthcare-associated methicillin-resistant Staphylococcus aureus bacteremia in the propensity-matched analyses
| Â | Empirical antibiotic therapy | In-hospital mortality, n (%) | OR (95Â % CI) | MRSA-related mortality, n (%) | OR (95Â % CI) |
|---|---|---|---|---|---|
Severe sepsis or septic shock (n = 75) | |||||
 Yes | Appropriate | 24 (57.1) | 1.02 (0.41–2.56) | 13 (31.0) | 1.12 (0.42–2.96) |
| Â | Inappropriate | 19 (57.9) | 11 (33.3) | ||
 No | Appropriate | 18 (21.2) | 1.21 (0.60–2.43) | 6 (7.1) | 1.57 (0.54–4.51) |
| Â | Inappropriate | 23 (24.5) | 10 (10.6) | ||
Septic shock (n = 45) | |||||
 Yes | Appropriate | 20 (66.7) | 1.00 (0.27–3.72) | 12 (40.0) | 1.00 (0.28–3.54) |
| Â | Inappropriate | 10 (66.7) | 6 (40.0) | ||
 No | Appropriate | 22 (22.7) | 1.36 (0.73–2.55) | 7 (7.2) | 1.99 (0.78–5.10) |
| Â | Inappropriate31 | 32 (28.6) | 15 (13.4) | ||
Charlson’s comorbidity index ≥3 (n = 108) |  |  |  | ||
 Yes | Appropriate | 31 (56.4) | 0.62 (0.29–1.32) | 13 (23.6) | 0.83 (0.33–2.05) |
| Â | Inappropriate | 24 (44.4) | Â | 11 (20.8) | Â |
 No | Appropriate | 11 (15.3) | 1.82 (0.79–4.18) | 6 (8.3) | 1.75 (0.60–5.09) |
| Â | Inappropriate | 18 (24.7) | Â | 10 (13.7) | Â |