From: Factors associated with 10 years of continuous viral load suppression on HAART
Characteristic | All | Continuous VL suppression | Non-continuous VL suppression | P-value |
---|---|---|---|---|
Number of participants, n | 276 | 149 | 127 | – |
Gender, Male | 252 (91 %) | 137 (92 %) | 115 (91 %) | 0.845 |
Race | – | – | – | 0.234 |
Caucasian | 119 (43 %) | 70 (47 %) | 49 (39 %) | – |
African-American | 126 (46 %) | 61 (41 %) | 65 (51 %) | – |
Hispanic/Other | 31 (11 %) | 18 (12 %) | 13 (10 %) | – |
Median Year of HIV Diagnosis | 1993 (1989,1998) | 1996 (1991, 2000) | 1991 (1987, 1994) | <0.001 |
Median Age at HIV Diagnosis, years | 31 (26,38) | 32 (28,38) | 30 (25, 37) | 0.065 |
Median Year of HAART Initiation | 1997 (1996,1999) | 1998 (1997,2001) | 1997 (1996,1998) | <0.001 |
HAART Era at Initiation | – | – | – | <0.001 |
1996–1999 | 212 (77 %) | 98 (66 %) | 114 (90 %) | – |
2000–2003 | 64 (23 %) | 51 (34 %) | 13 (10 %) | – |
Median Age at First HAART, years | 37 (32,42) | 37 (32,41) | 37 (31,42) | 0.807 |
Median CD4 Count at First HAART, cells/uL | 319 (200, 458) | 375 (256, 499) | 261 (146,400) | <0.001 |
Median VL at first HAART, log10 copies/mL | 4.5 (3.6,4.9) | 4.4 (3.5, 4.9) | 4.5 (3.8, 5) | 0.048 |
AIDS before first HAART | 27 (10 %) | 12 (8 %) | 15 (12 %) | 0.399 |
First HAART Regimen | – | – | – | <0.001 |
3 NRTI | 14 (5 %) | 12 (8 %) | 2 (2 %) | – |
Boosted PI | 20 (7 %) | 7 (5 %) | 13 (10 %) | – |
NNRTI | 53 (19 %) | 43 (29 %) | 10 (8 %) | – |
PI + NNRTI + NRTI | 16 (6 %) | 11 (7 %) | 5 (4 %) | – |
Unboosted PI | 173 (63 %) | 76 (51 %) | 97 (76 %) | – |
Non-HAART ARV Use Before HAART | 160 (58 %) | 55 (37 %) | 105 (83 %) | <0.001 |
History of HBV Infection Before First HAART | 125 (45 %) | 60 (40 %) | 65 (51 %) | 0.090 |
History of HCV Infection Before First HAART | 12 (4 %) | 5 (3 %) | 7 (6 %) | 0.562 |