Fig. 3

Evolution of the clinical features of HFMD/HA inpatients admitted to Zhujiang Hospital between 2010 and 2013. SCNSI: severe central nervous system involvement; HFMD/HA: hand, foot, and mouth disease/herpangina; CNSI: central nervous system involvement; ARI: acute respiratory infection; SARI: severe acute respiratory infection; AMI: acute myocardial injury; AHI: acute hepatic injury. Title: the relationship of enterovirus serotype constituent ratios and the clinical features of infected children. We observed the phenomneon of obvious change of clinical features of children infected with enterovirus and a notable change of enterovirus serotype constituent ratios in Guangdong province, China during 2010–2013, which suggested that change of enterovirus serotype constituent ratios might be responsible for the phenomenon of obvious change of clincial features of children infected with enterovirus