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Table 3 In vitro susceptibilities of Candida parapsilosis complex isolates considered in this study

From: Factors related to outcome of bloodstream infections due to Candida parapsilosis complex

Antifungal agents MIC range (μg/ml) MIC50 (μg/ml) MIC90 (μg/ml) % of isolates in the indicated category according to CLSIa
  S SDD I R WT Non-WT
Amphotericin B ≤0.12–1 0.5 0.5 - - - - 100 0
Flucytosine ≤0.06–1 ≤0.06 0.25 - - - - 97 3
Fluconazole ≤0.12–4 0.25 1 98.4 1.6 - 0 - -
Itraconazole ≤0.015–0.25 0.06 0.12 - - - - 100 0
Voriconazole ≤0.008–0.06 ≤0.008 0.015 100 0 - 0 - -
Posaconazole ≤0.008–0.12 0.03 0.06 - - - - 100 -
Caspofungin 0.06–1 0.25 0.5 100 - 0 0 - -
Anidulafungin 0.12–2 0.5 2 100 - 0 0 - -
Micafungin 0.12–2 1 2 100 - 0 0 - -
  1. aCategory was interpreted according to CLSI breakpoints as reported in ref. 15. S, susceptible; SDD susceptible dose dependent, I intermediate, R resistant, WT wild type