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Table 3 In vitro susceptibilities of Candida parapsilosis complex isolates considered in this study

From: Factors related to outcome of bloodstream infections due to Candida parapsilosis complex

Antifungal agents

MIC range (μg/ml)

MIC50 (μg/ml)

MIC90 (μg/ml)

% of isolates in the indicated category according to CLSIa

 

S

SDD

I

R

WT

Non-WT

Amphotericin B

≤0.12–1

0.5

0.5

-

-

-

-

100

0

Flucytosine

≤0.06–1

≤0.06

0.25

-

-

-

-

97

3

Fluconazole

≤0.12–4

0.25

1

98.4

1.6

-

0

-

-

Itraconazole

≤0.015–0.25

0.06

0.12

-

-

-

-

100

0

Voriconazole

≤0.008–0.06

≤0.008

0.015

100

0

-

0

-

-

Posaconazole

≤0.008–0.12

0.03

0.06

-

-

-

-

100

-

Caspofungin

0.06–1

0.25

0.5

100

-

0

0

-

-

Anidulafungin

0.12–2

0.5

2

100

-

0

0

-

-

Micafungin

0.12–2

1

2

100

-

0

0

-

-

  1. aCategory was interpreted according to CLSI breakpoints as reported in ref. 15. S, susceptible; SDD susceptible dose dependent, I intermediate, R resistant, WT wild type