Clinical relevance of molecular identification of microorganisms and detection of antimicrobial resistance genes in bloodstream infections of paediatric cancer patients

Table 4 Phenotypic susceptibility, molecular tests and antimicrobial therapy of patients with death related to BSI

Episode	Underlying disease	Method		Phenotypic susceptibility			Resistance gene	Antimicrobial therapy
Episode	Underlying disease	Phenotypic	Molecular	Cefepime	Meropenen	Vancomycin	Resistance gene	Period 1	Period 2
5	AML	E. coli	Negative	Resistant	Susceptible	NA	Neg	Modified	Adequate
31	Other	C. tropicalis	Candida spp.	NA	NA	NA	NA	Adequate	Adequate
46	Wilms’ tumour	P. aeruginosa	P. aeruginosa	Resistant	Resistant	NA	bla _SPM	Modified	Inadequate
56	ALL	C. lusitanae	Negative	NA	NA	NA	NA	Modified	Inadequate
58	ALL	P. aeruginosa	Negative	Resistant	Resistant	NA	Neg	Modified	Adequate
69	RMS	E. faecium	Enterococcus spp.	NA	NA	Resistant	vanA	Modified	Inadequate

ALL acute lymphoid leukaemia, RMS Rhabdomyosarcoma, Neg negative, NA not applicable

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