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Table 5 The influence on cytokines (interleukins and TNF-α)

From: The efficacy of thymosin α1 as immunomodulatory treatment for sepsis: a systematic review of randomized controlled trials

Cytokines

Included studies

Cases

Chi

I2 %

SMD

95 % CI

P

IL-6

4 [27, 28, 34, 41]

189

28

89 %

−0.32

−1.24,0.6

0.49

IL-10

3 [27, 28, 34]

129

2.63

24 %

1.06

0.64,1.49

<0.00001

TNF-α

4 [28, 29, 34, 35]

190

2.55

0 %

−0.47

−0.76,–0.18

0.002