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Table 3 Epidemiological and clinical differences between children with (VIKIA+) and without rotavirus. Univariate and Multivariate analysis

From: Multicenter prospective study on the burden of rotavirus gastroenteritis in children less than 3 years of age in Spain

  

Univariate analysis

Multivariate analysis (N = 375)

  

N

OR

IC 95 %

p-value

OR

CI 95 %

p-value

Gender

Male

453

  

0.080

   

Female

1.395

0.961–2.023

0.080

   

Age (months)

454

0.978

0.957–0.999

0.038

0.984

0.958–1.010

0.215

RV Vaccination

Complete vaccination

444

  

<0.001

  

<0.001

Partial vaccination

0.685

0.143–3.278

0.636

0.751

0.144–3.919

0.735

No vaccination

5.649

3.316–9.625

<0.001

5.758

3.196–10.374

<0.001

Breastfeeding

No

452

  

0.138

   

Yes

1.467

0.884–2.435

0.138

   

Attendance at day care centre

No

449

  

0.021

   

Yes

0.641

0.440–0.934

0.021

   

Fever 24 h. befote the visit

No

453

  

<0.001

  

0.018

Yes

2.208

1.512–3.223

<0.001

1.779

1.103–2.868

0.018

Number of episodes of vomiting 24 h. before the visit

423

1.246

1.138–1.363

<0.001

1.112

1.000–1.236

0.050

Number of depositions 24 h. before the visit

448

1.004

0.953–1.059

0.873

   

Dehydration 24 h. before the visit

No

448

  

<0.001

   

Yes

3.111

1.737–5.569

<0.001

   

Rehydratation treatment 24 h. before the visit

No

419

  

0.004

  

0.170

Yes

1.806

1.209–2.698

0.004

1.413

0.862–2.316

0.170

Fever returning at the follow-up

No

412

  

0.037

   

Yes

1.520

1.026–2.252

0.037

   

Number of daily episodes of vomiting during the follow-up

446

1.219

1.111–1.338

<0.001

   

Maximum number of daily depositions during the follow-up

454

1.085

1.024–1.149

0.005

   

Grade of dehydration during the follow-up

A

322

  

0.110

   

B

8.207

0.998–67.456

0.050

   

C

1.565

0.530–4.621

0.417

   

Hospitalization

No

449

  

0.108

   

Yes

2.094

0.850–5.157

0.108

   

Visits general practitioner/paediatrician

No

429

  

0.347

   

Yes

1.466

0.660–3.255

0.347

   

Visits to emergency department

No

358

  

<0.001

   

Yes

2.134

1.361–3.345

<0.001

   

Phone consultations

No

337

  

0.231

   

Yes

1.335

0.832–2.142

0.231

   

Child´s behaviour: Cries more

No

449

  

<0.001

   

Yes

2.621

1.756–3.912

<0.001

   

Child´s behaviour: is more irritable

No

449

  

<0.001

   

Yes

2.184

1.445–3.303

<0.001

   

Child´s behaviour: Plays less

No

446

  

<0.001

   

Yes

2.702

1.816–4.019

<0.001

   

Child´s behaviour: Is more tired

No

449

  

<0.001

  

0.002

Yes

2.909

1.921–4.405

<0.001

2.277

1.357–3.819

0.002

Impact on the parents: worried because of the symptoms

No

451

  

0.092

   

Yes

3.038

0.836–11.040

0.092

   

Impact on the parents: Sleep disturbance

No

451

  

0.043

   

Yes

1.824

1.020–3.262

0.043

   

Impact on the parents: Need of external aid

No

448

  

0.002

   

Yes

1.839

1.246–2.715

0.002

   

Impact on the parents: Alteration of the working rhythm

No

449

  

<0.001

  

0.264

Yes

2.154

1.429–3.245

<0.001

1.351

0.797–2.290

0.264

Impact on the parents: Loss of working days

No

451

  

0.076

   

Yes

1.508

0.958–2.376

0.076

   
  1. OR Odds Ratio, CI 95 % 95 % Confidence interval
  2. Dependent variable of logistic regression: Result of the VIKIA test for RV (Positive = 1/Negative = 0)