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Table 3 Outcome, management and laboratory findings in single virus infections

From: Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen

 

RSV

RV

hMPV

HCoV

FLU

HAdV

HBoV

PIV

p-value

N = 331 single pathogens

200

30

23

24

21

14

10

9

 

Hospitalization

 admission, n(%)

162(81.0)

22(73.3)

16(69.6)

10(41.7)

16(76.2)

10(71.4)

9(90.0)

7(77.8)

0.004a

 days, mean (SD)

4.4(2.8)

3.3(3.1)

3.2(1.5)

3.9(3.4)

2.9(2.7)

2.9(2.1)

3.2(1.9)

5.3(2.7)

0.014b

 median (IQR)

4.0 (4.0)

2.0(3.75)

3.0(2.0)

3.0(3.75)

2.0(1.75)

2.0(1.5)

3.0(1.5)

4.0(5.0)

 

Therapy

 AB initiated, n(%)

75(37.5)

7(23.3)

7(30.4)

4(16.7)

7(33.3)

1(7.1)

4(40.0)

6(66.7)

0.029a,c

 AB no of days, mean (SD)

2.4(3.3)

1.4(2.7)

2.4(3.9)

1.5(3.6)

2.0(3.0)

0.5(1.9)

2.8(3.6)

3.7(3.3)

0.091b

 median (IQR)

0.0(7.0)

0.0(0.8)

0.0(7.0)

0.0(0.0)

0.0(5.0)

0.0(0.0)

0.0(7.0)

3.0(7.0)

 

 Oxygen initiated,n(%)

106(53)

9(30)

9(39.1)

3(12.5)

6(28.6)

5(35.7)

7(60)

5(55.6)

0.062a,c

 Oxygen no of days, mean (SD)

2.4(2.7)

1.2(2.2)

1.5(1.7)

1.0(1.8)

0.9(1.5)

1.4(2.1)

1.6(1.3)

2.9(2.9)

0.052b

 median (IQR)

2.35(4.0)

0.0(2.5)

1.0(3.0)

0.0(2.3)

0.0(1.8)

0.5(2.5)

2.0(2.0)

3.0(5.0)

 

 Nebulizationd initiated n(%)

63(31.5)

6(20)

6(26.1)

0(0)

3(14.3)

4(28.6)

6(60)

3(33.3)

0.086a,c

 Nebulizationd, no of days, mean (SD)

1.2(2.0)

0.7(1.5)

0.8(1.3)

0.0(0.0)

0.4(0.9)

1.4(2.1)

2.2(2.2)

1.3(1.6)

0.050b

 median (IQR)

0.0(2.0)

0.0(1.0)

0.0(1.75)

0.0(0.0)

0.0(0.0)

0.0(2.75)

2.0(3.0)

0.0(3.0)

 

Laboratory

 CRP performed, n(%)

111(55.5)

16(33.0)

9(39.1)

14(58.3)

15(71.4)

7(50.0)

4(40.0)

2(22.2)

0.401a,c

 CRP max level, mean (SD), mg/L

23.1(25.4)

13.8(19.9)

71.0(117.7)

19.0(44.4)

16.6(18.8)

27.3(36.7)

23.7(26.3)

26.0(31.1)

0.440b

 median (IQR)

14.0(37.0)

5.0(25.5)

14.0(112.0)

0.0(14.5)

9.0(25.0)

7.0(63.0)

21.0(48)

26.0(44.0)

 

 CRP > 40, n(%), mg/L

27(13.5)

2(6.7)

3(13.0)

2(8.3)

2(9.5)

2(14.3)

2(20.0)

1(11.1)

0.706a,c

 WBC performed, n(%)

26(13.0)

3(10.0)

1(4.3)

0(0.0)

8(38.1)

1(7.1)

1(10.0)

1(11.1)

0.028a,c

 WBC max level, mean (SD), 109/L

11.6 (4.5)

9.5 (2.4)

7.6

.

8.1 (2.9)

12.7

13.6 (0.3)

27.0

0.065b

 median (IQR)

11.1(6.1)

9.4

7.6(0)

.

8.8(5.6)

12.7(0.0)

13.6(0.0)

27.0(0)

 
  1. AB antibiotics, CRP complement reactive protein, WBC white blood count
  2. Significant differences are noted as bold (highest) versus italic (lowest) when possible
  3. a Pearson Chi-square test
  4. b Kruskal Wallis test
  5. c interpret with caution as any cell has a value <5
  6. d Nebulization with salbutamol and ipratropium bromide