Table 6 Age-adjusted time trends in bloodstream infection (BSI) mortality stratified by sex. BSI rate ratios per calendar year by Poisson regression are shown

BSI, all

1.014 (0 .965–1.067)

0.58

0.974 (0.933–1.017)

0.23

 Community acquired

0.917 (0.838–1.002)

0.056

0.979 (0.8980–1.068)

0.64

 Health care-associated

1.074 (0.999–1.154)

0.052

0.982 (0.928–1.039)

0.53

 Hospital acquired

0.998 (0.882–1.129)

0.97

0.915 (0.825–1.015)

0.095

 Urinary tract

0.989 (0.893–1.095)

0.83

1.114 (1.001–1.239)

0.047

 Lungs

1.018 (0.908–1.140)

0.76

0.910 (0.838–0.988)

0.024

 Biliary tract

0.982 (0.740–1.303)

0.90

1.030 (0.867–1.226)

0.73

 Gastrointestinal tract

0.978 (0.800–1.195)

0.83

0.891 (0.724–1.097)

0.28

 Skin or soft tissue

1.007 (0.855–1.186)

0.93

0.994 (0.880–1.122)

0.92

 Other

0.913 (0.782–1.065)

0.25

1.024 (0.879–1.193)

0.76

 Unknown

1.086 (0.981–1.202)

0.11

0.922 (0.836–1.017)

0.10

 Gram-negative BSI

1.023 (0.953–1.098)

0.53

1.011 (0.941–1.085)

0.77

 Gram-positive BSI

0.999 (0.921–1.084)

0.99

0.937 (0.884–0.993)

0.027

 Polymicrobial or fungal BSI

0.952 (0.829–1.093)

0.49

1.072 (0.911–1.260)

0.40

  Escherichia coli

1.014 (0.911–1.129)

0.79

0.957 (0.964–1.060)

0.40

  Streptococcus pneumoniae

0.971 (0.812–1.161)

0.75

0.850 (0.745–0.971)

0.017

  Staphylococcus aureus

0.985 (0.880–1.103)

0.80

0.972 (0.882–1.070)

0.56

  Klebsiella spp.

1.169 (0.960–1.425)

0.12

1.107 (0.916–1.338)

0.29