Variable | TST-positive at baseline (n = 523) | TST Converter (n = 62) | ORa (95% CI) | P + | TST negative (n = 253) | ORb (95% CI)* | P ++ |
---|---|---|---|---|---|---|---|
Contact Factors | |||||||
Age (years) | 22 [12–41] | 15 [10–39] | 0.99 (0.97–1.00) | 0.17 | 18 [8–34] | 1.01 (0.99–1.03) | 0.24 |
Female | 292 (56) | 41 (66) | 1.58 (0.96–2.60) | 0.07 | 140 (55) | 1.70 (0.95–3.06) | 0.07 |
BCG scar present | 425 (81) | 54 (87) | 1.58 (0.96–2.60) | 0.32 | 207 (82) | 2.96 (1.01–8.67) | 0.05 |
Other TB contact | 127 (25) | 6 (10) | 0.36 (0.16—0.82) | 0.01 | 33 (13) | - | - |
IGRA negative | 78 (19) | 18 (31) | 1.73 (0.98–3.07) | 0.06 | 196 (84) | - | - |
Index Factors | |||||||
Age (years) | 34 [23–44] | 32 [22–39] | - | - | 37 [27–42] | 0.98 (0.94–1.01) | 0.15 |
Cough duration (weeks) | 8 [4–16] | 8 [4–12] | 0.96 (0.91–1.02) | 0.16 | 8 [4–16] | 0.97 (0.93–1.00) | 0.08 |
VACS | 8 [5–9] | 9 [8–10] | - | - | 5 [3–8.5] | 1.20 (1.03–1.40) | 0.02 |
Extent of disease on CxR1 | 257 (50) | 20 (32) | 0.87 (0.40–1.94) | 0.74 | 945 (38) | - | - |
Presence of cavities | 412 (80) | 40 (65) | 0.68 (0.22–2.05) | 0.49 | 163 (65) | 0.96 (0.40–2.29) | 0.93 |
Environmental Factors | |||||||
Own residence | 425 (81) | 60 (97) | 4.87 (1.05–22.5) | 0.04 | 238 (94) | - | - |
Sleep in the same room | 353 (67) | 46 (74) | - | - | 137 (54) | 2.22 (0.91–5.36) | 0.08 |
> 6 h / day of contact | 376 (73) | 46 (74) | - | - | 156 (62) | 1.37 (0.64–2.95) | 0.42 |