Table 1 Data on photosensitivity in doxycycline-treated patients with erythema migrans in Europe (Eu) and the United States (US)
From: Doxycycline-induced photosensitivity in patients treated for erythema migrans
First author, year | Eu/ US | Number of patients (% of female) | Doxycycline | Patients (%) with photosensitivity | |
|---|---|---|---|---|---|
Dosage | Days | ||||
Dattwyler, 1990 [7] | US | 37 (49%) | 100 mg twice daily | 21 | 1 (2.7%) |
Nadelman, 1992 [4] | US | 60 (42%) | 100 mg three times daily | 20 | 9 (15%) |
Massarotti, 1992 [8] | US | 22 (50%) | 100 mg twice daily | 10–20 | 1 (4.5%) |
Strle, 1992 [13] | Eu | 23 (57%) | 100 mg twice daily | 14 | 1 (4.3%) |
Strle, 1993 [11] | Eu | 52 (44%) | 100 mg twice daily | 14 | 6 (11.5%) |
Luger, 1995 [3] | US | 113 (37%) | 100 mg three times daily | 12–20 | 7 (6.2%) |
Strle, 1996 [12] | Eu | 42 (50%) | 100 mg twice daily | 14 | 5 (11.9%) |
Dattwyler, 1997 [6] | US | 72 (39%) | 100 mg twice daily | 21 | 9 (12%) |
Baršić, 2000 [10] | Eu | 40 (52%) | 100 mg twice daily | 14 | 0 |
Wormser, 2003 [5] | US | 61 (32%) | 100 mg twice daily | 10 | 5 (8.2%) |
59 (40%) | 20 | 2 (3.4%) | |||
Cerar, 2010 [9] | Eu | 145 (58%) | 100 mg twice daily | 15 | 1 (0.7%) |
Stupica, 2012 [14] | Eu | 108 (57%) | 100 mg twice daily | 10 | 0 |
117 (54%) | 15 | 7 (6%) | |||