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Table 1 Socio demographic and clinical characteristics of the study participants (N = 68,378)

From: Effect of isoniazid preventive therapy on tuberculosis incidence and associated risk factors among HIV infected adults in Tanzania: a retrospective cohort study

 

Total

Ever received

IPT

(n = 6454)

Never received IPT

(n = 61,924)

χ2-P-value*

Characteristic

n (%)

n (%)

 

Median Age in years (IQR)

35.0 (29.3–41.8)

36.8 (31.5–45.5)

34.7 (29–41.6)

0.001

Age category (years)

   

0.001

 15–25

7500 (11.0)

362 (5.6)

7138 (11.5)

 

 26–35

26,648 (39.0)

2250 (34.9)

24,398 (39.4)

 

 36–45

22,208 (32.5)

2468 (38.2)

19,740 (31.9)

 

 45+

12,022 (17.6)

1374 (21.3)

10,648 (17.2)

 

Sex

   

0.086

 Males

16,892 (24.7)

1651 (25.6)

15,241 (24.6)

 

 Females

51,486 (75.3)

4803 (74.4)

46,683 (75.4)

 

Marital status

   

0.001

 Single

19,249 (28.1)

1749 (27.1)

17,500 (28.3)

 

 Married/co-habiting

33,224 (48.6)

3094 (47.9)

30,130 (48.7)

 

 Widowed/divorced

8823 (12.9)

991 (15.4)

7832 (12.6)

 

BMI categories (Kg/m2)

   

0.001

 Underweight (< 18.5)

8054 (11.8)

815 (12.6)

7239 (11.7)

 

 Normal (18.5–24.5)

27,704 (40.5)

2984 (46.2)

24,720 (39.9)

 

 Overweight (25–29.9)

10,923 (16.0)

1136 (17.6)

9787 (15.8)

 

 Obese (≥30)

5446 (8.0)

547 (8.5)

4899 (7.9)

 

Mean BMI (SD)

23.3 (5.2)

23.2 (5.0)

23.2 (5.2)

0.534

CD4+ categories (cells/μl)

   

0.001

  < 200

12,891 (18.9)

1438 (22.3)

11,453 (18.5)

 

 200–350

9918 (14.5)

1317 (20.4)

8601 (13.9)

 

  > 350

14,585 (21.3)

1590 (24.6)

12,995 (21.0)

 

Median CD4+ cell count (IQR)

252 (118–491)

245 (119–390)

253 (119–417)

0.064

WHO staging for HIV/AIDS

   

0.001

 I

22,530 (32.9)

1411 (21.9)

20,664 (36.1)

 

 II

13,881 (20.3)

1587 (24.6)

11,652 (20.3)

 

 III

25,894 (37.9)

2952 (45.7)

19,957 (34.9)

 

 IV

4485 (6.6)

308 (4.8)

3666 (6.4)

 

Cotrimoxazole use

   

0.001

 Yes

63,041 (92.2)

6389 (99.0)

56,652 (91.5)

 

 No

5337 (7.8)

65 (1.0)

5272 (8.5)

 

ART use

   

0.001

 Yes

56,245 (82.3)

6214 (96.3)

50,031 (80.8)

 

 No

12,133 (17.7)

240 (3.7)

11,893 (19.2)

 

Functional status at enrolment

   

0.001

 Ambulatory

1449 (2.1)

58 (0.9)

1391 (2.2)

 

 Bedridden

381 (0.6)

35 (0.5)

346 (0.6)

 

 Working

66,070 (96.6)

6324 (98.0)

59,746 (96.5)

 

Health facility type

   

0.001

 Dispensary

25,858 (37.8)

165 (2.6)

25,693 (41.5)

 

 Health center

18,961 (27.7)

1836 (28.4)

17,125 (27.7)

 

 Hospital

21,407 (31.3)

4435 (68.7)

16,972 (27.4)

 

Health facility ownership

    

 Government (Public)

60,596 (88.6)

6338 (98.2)

54,258 (87.6)

0.001

 Private/FBO

6590 (9.7)

108 (1.7)

6482 (10.5)

 
  1. Some variables had missing records *Chi-squared P-value