Table 3 Comparison of Clinical Outcomes of S. aureus bacteremia by qSOFA score
Clinical Outcomes | High qSOFA n = 90 (%) | Low qSOFA n = 312 (%) | p value |
|---|---|---|---|
ICU admission | 58 (64) | 67 (21) | < 0.0001 |
ICU admission within 48 h of first positive culture | 51 (57) | 50 (16) | < 0.0001 |
Need for vasopressors | 31 (35) | 17 (6) | < 0.0001 |
Duration of ICU stay, daysa | 5 (2, 12.3) | 3 (1, 7) | 0.01 |
Duration of ICU stay > 72 h | 43 (48) | 38 (12) | < 0.0001 |
Day 4 Success | 45 (50) | 228 (73) | < 0.0001 |
 Died | 2 (4) | 2 (1) | 0.07 |
Day 4 Failure | 44 (49) | 83 (27) | < 0.0001 |
 Died | 15 (34) | 7 (8) | 0.0003 |
Microbial Persistence on day 4 | 31 (34) | 62 (20) | 0.0039 |
 Died | 10 (32) | 3 (5) | 0.0007 |
Initial GCS < 15 | 54/89 (61) | 31/306 (10) | < 0.0001 |
 Died | 13 (24) | 2 (6) | 0.04 |
Initial SBP ≤ 100 mmHg | 57/84 (68) | 52/297 (18) | < 0.0001 |
 Died | 12 (21) | 3 (6%) | 0.026 |
Initial RR ≥ 22 breaths per minute | 72/85 (85) | 71/298 (24) | < 0.0001 |
 Died | 14 (19) | 4 (6) | 0.021 |
30-day mortality | 17 (19) | 9 (3) | < 0.0001 |
Total Hospital LOS, days a | 16 (8, 32) | 10 (6, 19) | < 0.0001 |
LOS after first positive culture, days a | 14 (7.8, 23) | 9 (6.25, 17) | 0.001 |
Disposition of survivors | N = 73 | N = 303 | 0.92 |
 Home | 48 (66) | 198 (65) |  |
 Skilled nursing facility | 12 (16) | 47 (16) |  |
 Outside Hospital | 4 (5) | 23 (8) |  |
 Rehab center | 7 (10) | 23 (8) |  |
 Homeless/jail | 2 (3) | 12 (4) |  |