Studies included | Country | Mycoplasma pneumonia patients | Control group | Mycoplasma pneumonia patients included in the staging | Detection method | Company of the reagent source | Gold standard | Blind | Value of the positive judgment | Results | FN | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TP | FP | TN | |||||||||||
Ryoichi Saito, 2005 | Japan | 6 | 89 | No | LAMP | 1.Roche Diagnostics | Real-time PCR | yes | 2 × 10 2 | 6 | 0 | 89 | 0 |
2.Qiagen | |||||||||||||
3.Applied Biosystems | |||||||||||||
FEI ZHAO, 2013 | China | 21 | 59 | No | LAMP | Qiagen | Real-time PCR | yes | unclear | 21 | 5 | 54 | 0 |
Amy E. Ratliff II, 2014 | American | 22 | 192 | No | LAMP | 1.Qiagen | Real-time PCR | yes | C T ≤ 42.0 | 22 | 2 | 190 | 0 |
2.Agilent | |||||||||||||
Brianna L. Petrone, 2015 | American | 226 | 26 | No | LAMP | 1.Roche Applied Science | Real-time PCR | yes | CT < 30 | 200 | 1 | 25 | 26 |
2.Thermo Scientific | |||||||||||||
3.MP Biomedicals | |||||||||||||
Brianna L. Petrone, 2015 | American | 39 | 33 | No | LAMP | 1.Roche Applied Science | Real-time PCR | yes | CT ≥ 30 | 32 | 0 | 33 | 7 |
2.Thermo Scientific | |||||||||||||
3.MP Biomedicals | |||||||||||||
Fujio Kakuya, 2017 | Japan | 58 | 43 | NO | LAMP | 1.Eiken Chemical | Real-time PCR | Yes | an MP DNA load of> = 4.5 copies/μL | 15 | 0 | 43 | 0 |
2.Asahi Kasei Pharma | |||||||||||||
Fujio Kakuya, 2017 | Japan | 58 | 50 | NO | LAMP | 1.Eiken Chemical | Real-time PCR | Yes | an MP DNA load of> = 4.5 copies/μL | 8 | 0 | 43 | 7 |
2.Asahi Kasei Pharma | |||||||||||||
Ho Namkoong, 2018 | Japan | 73 | 84 | No | LAMP | 1. Mizuho Medy | Real-time PCR | yes | unclear | 70 | 1 | 83 | 3 |
1. Fujifilm | |||||||||||||
2. Asahi Kasei Pharma | |||||||||||||
Xin Yuan, 2018 | China | 116 | 9 | No | LAMP | 1. Oxoid | Real-time PCR | yes | unclear | 37 | 6 | 3 | 79 |
2. New England Biolabs | |||||||||||||
3. Da An Gene Co, | |||||||||||||
4. Sinopharm Chemical Reagents | |||||||||||||
5. Shanghai Simco Biotech | |||||||||||||
6. Beijing Mylab Corporation |