TruCulture® tube | Stimulus | Immune response |
---|---|---|
1 | Heat killed Candida albicans | Whole microbe providing complex immune response, including activation of TLR6 |
2 | Lipopolysaccharide from E.coli (LPS) | Bacterial endotoxin. Activator of TLR4. |
3 | Resiquimod R848 | Synthetic agonist of TLR7 and TLR8 (both responding to single-stranded RNA) |
4 | Polyinosinic:polycytidylic acid (Poly I:C) | Analogue of double-stranded RNA. Activator of TLR3 |
5 | None (negative control) | Allows for assessment of in vivo activation |