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Table 5 Oxidative stress Biomarkers with MSP2 alleles

From: Severe oxidative stress in sickle cell disease patients with uncomplicated Plasmodium falciparum malaria in Kampala, Uganda

 

MDA (μM)

GSH (μM)

GPx (Units/ml)

CAT (U/mg prot)

SCD Malaria (n)

25

25

25

25

 IC3D7

1.57 ± 0.09

0.74 ± 0.01

0.38 ± 0.01

3.67 ± 0.29

 FC27

1.56 ± 0.08

0.75 ± 0.01

0.34 ± 0.02

3.31 ± 0.21

 P value a

0.9420

0.3705

0.0959

0.3298

Malaria

 IC3D7

1.43 ± 0.06

0.75 ± 0.01

0.43 ± 0.02

2.87 ± 0.19

 FC27

1.46 ± 0.08

0.74 ± 0.01

0.41 ± 0.02

3.25 ± 0.31

 P value a

0.7571

0.6099

0.3689

0.3041

 P value b

0.2382

0.3859

0.0400**

0.0282**

 P value c

0.3813

0.6112

0.0267**

0.8896

  1. MDA is malondialdehyde; GSH is reduced glutathione; GPx is Glutathione peroxidase; CAT is catalase. IC3D7 and FC27 are allele families of MSP2, *** Statistically significant. aBetween IC3D7 and FC27 in each group; b Between IC3D7 in SCD malaria and malaria groups; C Between FC27 in SCD malaria and malaria groups