Skip to main content

Table 5 Oxidative stress Biomarkers with MSP2 alleles

From: Severe oxidative stress in sickle cell disease patients with uncomplicated Plasmodium falciparum malaria in Kampala, Uganda

  MDA (μM) GSH (μM) GPx (Units/ml) CAT (U/mg prot)
SCD Malaria (n) 25 25 25 25
 IC3D7 1.57 ± 0.09 0.74 ± 0.01 0.38 ± 0.01 3.67 ± 0.29
 FC27 1.56 ± 0.08 0.75 ± 0.01 0.34 ± 0.02 3.31 ± 0.21
P value a 0.9420 0.3705 0.0959 0.3298
Malaria
 IC3D7 1.43 ± 0.06 0.75 ± 0.01 0.43 ± 0.02 2.87 ± 0.19
 FC27 1.46 ± 0.08 0.74 ± 0.01 0.41 ± 0.02 3.25 ± 0.31
P value a 0.7571 0.6099 0.3689 0.3041
P value b 0.2382 0.3859 0.0400** 0.0282**
P value c 0.3813 0.6112 0.0267** 0.8896
  1. MDA is malondialdehyde; GSH is reduced glutathione; GPx is Glutathione peroxidase; CAT is catalase. IC3D7 and FC27 are allele families of MSP2, *** Statistically significant. aBetween IC3D7 and FC27 in each group; b Between IC3D7 in SCD malaria and malaria groups; C Between FC27 in SCD malaria and malaria groups