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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease

Fig. 3

Combined data for the serial Magnesium/Calcium levels in the clinical trial and the observational cohort. Legends: In the observational cohort Mg/Ca levels were only measured in patients receiving MgSO4. Black bar = median value; n = number of patients assessed. Dashed green line: Potentially toxic levels for hypermagnesemia and hypocalcemia. D0 = baseline values, Mid-point = values measured 8–16 h after commencing the study drug. Other values (D1, D2, D3) were measured at 8–10 am on the relevant study day. By study day 3 a number of the trial patients had completed 72 h of the intervention and were already being weaned off their study drug. Patients in the observational cohort generally stopped MgSO4 after 48 h

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