Number of patients with event | ||
---|---|---|
Placebo (n = 12) | MgSO4 (n = 14) | |
Clinical events | ||
All adverse eventsa | 21 / 10 (83) | 22 / 10 (71) |
Fever | 6 | 7 |
Diminished deep tendon reflexes | 2 | 3 |
Coma / lethargy / irritability | 2 | 1 |
Respiratory problems | 3 | 4 |
Reduced urine output (< 1 ml/kg/hr for 4 h) | 4 | 5 |
Otherb,c | 4 | 2 |
Serious adverse events (Grades 3 and 4)a | 3 / 2 (17) | 3 / 3 (21) |
Coma | 1 | 0 |
Respiratory distress | 2 | 3 |
Laboratory events | ||
All adverse eventsa | 46 / 12 (100) | 51 / 13 (93) |
Respiratory Acidosis | 0 | 3 |
Respiratory Alkalosis | 8 | 6 |
Abnormal CK-MB | 7 | 9 |
Abnormal Creatinine | 2 | 2 |
Abnormal Hb | 4 | 4 |
Hyperkalemia | 2 | 0 |
Hypokalemia | 5 | 2 |
Hyponatremia | 9 | 9 |
Abnormal Troponin I | 5 | 5 |
Serious adverse events (Grades 3 and 4)a | 16 / 8 (67) | 21 / 10 (71) |
Respiratory Acidosis | 0 | 1 |
Respiratory Alkalosisd | 3 | 6 |
Abnormal CK-MB | 1 | 0 |
Abnormal Hb | 1 | 0 |
Hypokalemia | 1 | 1 |
Hyponatremiae | 5 | 7 |
Abnormal Troponin I | 5 | 4 |