Table 2 Clinical and programmatic characteristics of the patients treated for multi-drug resistant tuberculosis in Ethiopia between 2009 and 2014 (N = 751)
Variables | Frequency | Percent (%) |
|---|---|---|
Model of care | ||
Ambulatory | 178 | 23.7 |
Hospitalized | 573 | 76.3 |
TB treatment supporter | ||
Yes | 399 | 53 |
Missing/unknown | 43 | 6 |
No | 309 | 41 |
Type of TB treatment supporter | ||
HCW | 19 | 4.8 |
Family | 359 | 90 |
Other | 21 | 5.2 |
Co-morbidity (at least one) | ||
Yes | 293 | 39 |
Unknown | 65 | 8.7 |
No | 393 | 52.3 |
HIV status | ||
Reactive | 164 | 21.8 |
Non-reactive | 587 | 78.2 |
Diabetes mellitus | ||
Yes | 26 | 3.5(*6.7) |
No | 361 | 48(*93.3) |
Unknown | 364 | 48.5 |
Body mass index (kg/m2) at start of treatment | ||
< 18.5 | 313 | 41.8 |
Unknown | 296 | 39.4 |
> =18.5 | 142 | 18.8 |
Treatment interruption during treatment | ||
Yes | 28 | 3.7 |
No | 669 | 89.1 |
Missing | 54 | 7.2 |
Medication changed | ||
No | 248 | 33 |
Unknown | 432 | 57.5 |
Yes | 71 | 9.5 |
Reason for medication changed | ||
Side effect | 62 | 87.3 |
National algorithm change | 3 | 4.2 |
Others | 6 | 8.5 |
Pulmonary tuberculosis | ||
Smear positive | 542 | 72 |
Smear negative | 209 | 28 |
Bacilli load | ||
Scanty | 15 | 2.8 |
+ | 119 | 22 |
++ | 155 | 28.6 |
+++ | 107 | 19.7 |
Unknown | 146 | 26.9 |
Previous history of susceptible TB treatment | ||
Yes | 730 | 97.2 |
No | 21 | 2.8 |
Frequency of susceptible TB treatment | ||
One | 158 | 21.6 |
Two | 400 | 54.8 |
> =Three | 172 | 23.6 |
Resistance to | ||
Four drugs (RHES) | 167 | 22.2 |
Three drugs (RES/RHE) | 57 | 7.6 |
Only two drugs (RH) | 366 | 48.8 |
Only one drug (R) | 161 | 21.4 |
Category of the patient at start of treatment | ||
Failure | 555 | 73.9 |
Relapse | 70 | 9.3 |
LTFU & Other | 105 | 14 |
New | 21 | 2.8 |
History of hypokalemia | ||
Yes | 341 | 45.4 |
Missing/unknown | 90 | 12 |
No | 320 | 42.6 |
Treatment outcome of FL treatment | ||
Unsuccessful | 645 | 88.4 |
Successful | 85 | 11.6 |
Base line x-rays done | ||
Yes | 470 | 62.5 |
No | 148 | 19.7 |
Missing | 133 | 17.8 |
X-ray result/finding | ||
Abnormal | 426 | 90.6 |
Unknown | 30 | 6.4 |
Normal | 14 | 3 |
History of second line drug | ||
Yes | 15 | 2 |
No | 736 | 98 |